Int J Cardiol. 2010 Jul 9;142(2):195-6. doi: 10.1016/j.ijcard.2008.11.112. Epub 2008 Dec 17.
Preliminary studies suggest that left atrial appendage (LAA) closure might be beneficial in the prevention of stroke in patients with atrial fibrillation (AF). We evaluated the preliminary clinical efficacy of percutaneous LAA closure using the PLAATO-device (ev3 Endovascular, Inc., North Plymouth, MN) and found that none of the patients suffered from thrombo-embolic events within a time period of 2 years after successful LAA closure. Therefore, we believe that percutaneous closure of the LAA might be a valuable technique for AF patients with contra-indications for or failure of oral anticoagulation to prevent thrombo-embolic events.
初步研究表明，左心耳（LAA）封堵可能有益于预防房颤（AF）患者的中风。我们评估了使用 PLAATO 装置（ev3 Endovascular，Inc.，North Plymouth，MN）经皮 LAA 封堵的初步临床疗效，发现成功封堵 LAA 后 2 年内无 1 例患者发生血栓栓塞事件。因此，我们认为对于有抗凝禁忌或口服抗凝失败的 AF 患者，经皮 LAA 封堵可能是一种有价值的技术，可预防血栓栓塞事件。
