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Perfusion-sensitive MR imaging of gliomas: comparison between gradient-echo and spin-echo echo-planar imaging techniques.胶质瘤的灌注敏感磁共振成像：梯度回波与自旋回波平面回波成像技术的比较
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Glial tumor grading and outcome prediction using dynamic spin-echo MR susceptibility mapping compared with conventional contrast-enhanced MR: confounding effect of elevated rCBV of oligodendrogliomas [corrected].与传统对比增强磁共振成像相比，利用动态自旋回波磁共振磁化率成像进行胶质肿瘤分级及预后预测：少突胶质细胞瘤相对脑血容量升高的混杂效应[校正后]
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Spin-echo echo-planar perfusion prior to chemoradiation is a strong independent predictor of progression-free and overall survival in newly diagnosed glioblastoma.放化疗前的自旋回波平面灌注是新诊断胶质母细胞瘤无进展生存期和总生存期的强有力独立预测指标。
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本文引用的文献

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Pathogenesis and vascular integrity of breast cancer brain metastasis.乳腺癌脑转移的发病机制及血管完整性
Int J Cancer. 2007 Mar 1;120(5):1023-6. doi: 10.1002/ijc.22388.
2
The three-dimensional microvascular architecture of the human Kaposi sarcoma implanted in nude mice: a SEM corrosion casting study.植入裸鼠的人卡波西肉瘤的三维微血管结构：扫描电镜腐蚀铸型研究
Microvasc Res. 2006 Nov;72(3):128-35. doi: 10.1016/j.mvr.2006.06.001. Epub 2006 Aug 22.
3
Relative cerebral blood volume maps corrected for contrast agent extravasation significantly correlate with glioma tumor grade, whereas uncorrected maps do not.校正造影剂外渗后的相对脑血容量图与胶质瘤肿瘤分级显著相关，而未校正的图则不然。
AJNR Am J Neuroradiol. 2006 Apr;27(4):859-67.
4
Perfusion and diffusion MR imaging in enhancing malignant cerebral tumors.增强型恶性脑肿瘤的灌注与扩散磁共振成像
Eur J Radiol. 2006 Jun;58(3):394-403. doi: 10.1016/j.ejrad.2005.12.032. Epub 2006 Mar 9.
5
Vessel size imaging in humans.人体血管大小成像。
Magn Reson Med. 2005 Mar;53(3):553-63. doi: 10.1002/mrm.20383.
6
Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging.通过使用基于动态磁敏感对比增强磁共振成像得出的定量血容量测量值来鉴别低级别少突胶质细胞瘤与低级别星形细胞瘤。
AJNR Am J Neuroradiol. 2005 Feb;26(2):266-73.
7
Brain metastasis from colorectal cancer.结直肠癌脑转移
Int J Colorectal Dis. 2005 Jan;20(1):57-61. doi: 10.1007/s00384-004-0631-3. Epub 2004 Aug 11.
8
Dynamic, contrast-enhanced perfusion MRI in mouse gliomas: correlation with histopathology.小鼠胶质瘤的动态对比增强灌注磁共振成像：与组织病理学的相关性
Magn Reson Med. 2003 May;49(5):848-55. doi: 10.1002/mrm.10446.
9
Dynamic contrast-enhanced MRI: differentiating melanoma and renal carcinoma metastases from high-grade astrocytomas and other metastases.动态对比增强磁共振成像：鉴别黑色素瘤及肾癌转移灶与高级别星形细胞瘤及其他转移灶
Neuroradiology. 2003 Jan;45(1):44-9. doi: 10.1007/s00234-002-0886-8. Epub 2002 Dec 7.
10
Perfusion-sensitive MR imaging of gliomas: comparison between gradient-echo and spin-echo echo-planar imaging techniques.胶质瘤的灌注敏感磁共振成像：梯度回波与自旋回波平面回波成像技术的比较
AJNR Am J Neuroradiol. 2001 Aug;22(7):1306-15.

自旋回波平面回波灌注磁共振成像在孤立性强化脑病变鉴别诊断中的应用：鉴别孤立性转移瘤与原发性胶质瘤

Spin-echo echo-planar perfusion MR imaging in the differential diagnosis of solitary enhancing brain lesions: distinguishing solitary metastases from primary glioma.

作者信息

Young G S, Setayesh K

机构信息

Department of Radiology of Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

出版信息

AJNR Am J Neuroradiol. 2009 Mar;30(3):575-7. doi: 10.3174/ajnr.A1239. Epub 2008 Dec 18.

DOI:10.3174/ajnr.A1239
PMID:19095787
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7051437/
Abstract

Unlike the more widely reported gradient-echo echo-planar perfusion-weighted imaging (EPI-PWI) technique, spin-echo (SE) EPI relative cerebral blood volume maps select for blood volume in microvessels <8 microm in diameter. This first report of SE-EPI PWI for distinguishing brain metastasis from high-grade glioma demonstrated 88% sensitivity and 72% specificity in 83 patients. We discuss differences in microvessel architecture between high-grade glioma and brain metastasis that may explain the surprising success of SE-EPI in this application and may deserve further investigation.

摘要

与报道更为广泛的梯度回波平面回波灌注加权成像（EPI-PWI）技术不同，自旋回波（SE）EPI相对脑血容量图所选择的是直径<8微米的微血管中的血容量。这篇关于SE-EPI PWI用于鉴别脑转移瘤与高级别胶质瘤的首次报告显示，在83例患者中，其灵敏度为88%，特异度为72%。我们讨论了高级别胶质瘤与脑转移瘤在微血管结构上的差异，这些差异可能解释了SE-EPI在该应用中取得惊人成功的原因，可能值得进一步研究。