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Transforming growth factor-beta does not induce endothelin-1 secretion in primary cultured human tenon's fibroblasts.

作者信息

Hong Samin, Kim Chan Yun, Lee Jong Bok, Yoko Iizuka, Seong Gong Je

出版信息

Korean J Ophthalmol. 2008 Dec;22(4):276-7. doi: 10.3341/kjo.2008.22.4.276.

DOI:10.3341/kjo.2008.22.4.276
PMID:19096249
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2629916/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4238/2629916/558fc2d7434b/kjo-22-276-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4238/2629916/af6dd2205d3c/kjo-22-276-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4238/2629916/558fc2d7434b/kjo-22-276-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4238/2629916/af6dd2205d3c/kjo-22-276-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4238/2629916/558fc2d7434b/kjo-22-276-g002.jpg

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1
Transforming growth factor-beta does not induce endothelin-1 secretion in primary cultured human tenon's fibroblasts.转化生长因子-β不会诱导原代培养的人Tenon囊成纤维细胞分泌内皮素-1。
Korean J Ophthalmol. 2008 Dec;22(4):276-7. doi: 10.3341/kjo.2008.22.4.276.
2
Effect of growth factors on the activation of human Tenon's capsule fibroblasts.生长因子对人眼球筋膜囊成纤维细胞激活的影响。
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3
Brimonidine reduces TGF-beta-induced extracellular matrix synthesis in human Tenon's fibroblasts.布林佐胺可减少转化生长因子-β诱导的人眼Tenon 氏囊成纤维细胞细胞外基质的合成。
BMC Ophthalmol. 2015 May 28;15:54. doi: 10.1186/s12886-015-0045-8.
4
TGF-β1 stimulates human Tenon's capsule fibroblast proliferation by miR-200b and its targeting of p27/kip1 and RND3.TGF-β1 通过 miR-200b 及其对 p27/kip1 和 RND3 的靶向作用刺激人眼Tenon 囊成纤维细胞增殖。
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本文引用的文献

1
Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts.内皮素是人类肺成纤维细胞中对转化生长因子β促纤维化反应的下游介质。
Arthritis Rheum. 2007 Dec;56(12):4189-94. doi: 10.1002/art.23134.
2
A phase III study of subconjunctival human anti-transforming growth factor beta(2) monoclonal antibody (CAT-152) to prevent scarring after first-time trabeculectomy.一项关于结膜下注射人抗转化生长因子β（2）单克隆抗体（CAT - 152）预防初次小梁切除术后瘢痕形成的III期研究。
Ophthalmology. 2007 Oct;114(10):1822-30. doi: 10.1016/j.ophtha.2007.03.050.
3
Constitutive ALK5-independent c-Jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: evidence of an autocrine endothelin loop operating through the endothelin A and B receptors.
组成性非ALK5依赖的c-Jun氨基末端激酶激活导致肺纤维化中内皮素-1过表达：通过内皮素A和B受体起作用的自分泌内皮素环的证据。
Mol Cell Biol. 2006 Jul;26(14):5518-27. doi: 10.1128/MCB.00625-06.
4
RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis.靶向转化生长因子-βⅡ型受体的RNA干扰可抑制眼部炎症和纤维化。
Mol Vis. 2004 Oct 4;10:703-11.
5
Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery.评估抗转化生长因子-β2 抗体作为青光眼手术新型术后抗瘢痕形成药物的效果。
Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3394-401. doi: 10.1167/iovs.02-0978.
6
Antifibrotics and wound healing in glaucoma surgery.青光眼手术中的抗纤维化与伤口愈合
Surv Ophthalmol. 2003 May-Jun;48(3):314-46. doi: 10.1016/s0039-6257(03)00038-9.
7
Transforming growth factor-beta1 and ultraviolet A1 radiation increase production of vascular endothelial growth factor but not endothelin-1 in human dermal fibroblasts.转化生长因子-β1和紫外线A1辐射可增加人皮肤成纤维细胞中血管内皮生长因子的产生，但不会增加内皮素-1的产生。
Br J Dermatol. 2000 Sep;143(3):539-45. doi: 10.1111/j.1365-2133.2000.03707.x.
8
Indirect mitogenic effect of transforming growth factor-beta on cell proliferation of subconjunctival fibroblasts.转化生长因子-β对结膜下成纤维细胞增殖的间接促有丝分裂作用。
Invest Ophthalmol Vis Sci. 1998 Mar;39(3):481-6.
9
Molecular insights into renal interstitial fibrosis.肾间质纤维化的分子见解
J Am Soc Nephrol. 1996 Dec;7(12):2495-508. doi: 10.1681/ASN.V7122495.
10
Human placental endothelin: expression of endothelin-1 mRNA by human placental fibroblasts in culture.人胎盘内皮素：培养的人胎盘成纤维细胞中内皮素-1 mRNA 的表达
Mol Cell Endocrinol. 1995 Mar;109(1):119-23. doi: 10.1016/0303-7207(95)03493-q.