Aries P M, Gause A
Rheumatologie im Struenseehaus, Mörkenstr. 47, 22767, Hamburg-Altona.
Z Rheumatol. 2009 Feb;68(1):44-8. doi: 10.1007/s00393-008-0358-6.
The definition of outcome parameters has improved the care of vasculitis patients dramatically in recent decades. In the first phase of joint European studies, disease stages and activity were defined. In the second and third phases results of the randomized and controlled trials were summarized and published as European recommendations for the care of small and large vessel vasculitis. Irrespective of the type of vasculitis, inducing remission, maintaining remission and preventing disease- and therapy-related complications are the main outcome criteria.
近几十年来,结局参数的定义极大地改善了血管炎患者的治疗。在欧洲联合研究的第一阶段,对疾病阶段和活动进行了定义。在第二和第三阶段,随机对照试验的结果被总结并作为欧洲关于小血管和大血管血管炎治疗的建议发表。无论血管炎的类型如何,诱导缓解、维持缓解以及预防疾病和治疗相关并发症都是主要的结局标准。