来自巴西的含芬普雷司的进口减肥药：两例报告。
Imported fenproporex-based diet pills from Brazil: a report of two cases.
作者信息
Cohen Pieter A
机构信息
Department of Internal Medicine, Cambridge Health Alliance, Cambridge, MA, USA.
出版信息
J Gen Intern Med. 2009 Mar;24(3):430-3. doi: 10.1007/s11606-008-0878-4.
Banned amphetamine-based anorectics are illicitly imported into the United States (US), but little is known regarding the harm these diet pills pose to US residents. A 26-year-old woman using imported diet pills presented with a two-year history of intermittent chest pains, palpitations, headaches and insomnia. Urine toxicology screen detected amphetamines and benzodiazepines. Fenproporex and chlordiazepoxide were detected in her pills. Her symptoms resolved after she stopped using diet pills. A 38-year-old man using imported diet pills presented after his occupational urine screen was significantly positive for amphetamine. Fenproporex and fluoxetine were detected in his pills. These cases illustrate the potential harm from imported prescription diet pills that combine fenproporex with benzodiazepines, antidepressants, diuretics, laxatives and other substances. Increasing physicians' awareness of imported diet pill use may improve care of patients suffering from the pills' many adverse effects.
以苯丙胺为基础的违禁食欲抑制剂被非法进口到美国，但对于这些减肥药给美国居民带来的危害却知之甚少。一名使用进口减肥药的26岁女性有两年间歇性胸痛、心悸、头痛和失眠的病史。尿液毒理学筛查检测出苯丙胺和苯二氮卓类药物。在她服用的药丸中检测出芬普雷司和氯氮卓。她停止服用减肥药后症状得到缓解。一名使用进口减肥药的38岁男性在职业尿液筛查中苯丙胺呈显著阳性后前来就诊。在他服用的药丸中检测出芬普雷司和氟西汀。这些案例说明了将芬普雷司与苯二氮卓类药物、抗抑郁药、利尿剂、泻药及其他物质混合的进口处方减肥药的潜在危害。提高医生对进口减肥药使用情况的认识，可能会改善受减肥药诸多不良反应影响的患者的治疗。
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