Huo Donglai, Li Zhiqiang, Aboussouan Eric, Karis John P, Pipe James G
Keller Center for Imaging Innovation, Barrow Neurological Institute, Phoenix, Arizona 85013, USA.
Magn Reson Med. 2009 Jan;61(1):188-95. doi: 10.1002/mrm.21825.
Suppression of the fat signal in MRI is very important for many clinical applications. Multi-point water-fat separation methods, such as IDEAL (Iterative Decomposition of water and fat with Echo Asymmetry and Least-squares estimation), can robustly separate water and fat signal, but inevitably increase scan time, making separated images more easily affected by patient motions. PROPELLER (Periodically Rotated Overlapping ParallEL Lines with Enhanced Reconstruction) and Turboprop techniques offer an effective approach to correct for motion artifacts. By combining these techniques together, we demonstrate that the new TP-IDEAL method can provide reliable water-fat separation with robust motion correction. The Turboprop sequence was modified to acquire source images, and motion correction algorithms were adjusted to assure the registration between different echo images. Theoretical calculations were performed to predict the optimal shift and spacing of the gradient echoes. Phantom images were acquired, and results were compared with regular FSE-IDEAL. Both T1- and T2-weighted images of the human brain were used to demonstrate the effectiveness of motion correction. TP-IDEAL images were also acquired for pelvis, knee, and foot, showing great potential of this technique for general clinical applications.
磁共振成像(MRI)中脂肪信号的抑制对许多临床应用非常重要。多点水脂分离方法,如IDEAL(利用回波不对称性和最小二乘法进行水脂迭代分解),能够可靠地分离水和脂肪信号,但不可避免地会增加扫描时间,使分离后的图像更容易受到患者运动的影响。螺旋桨(PROPELLER,即具有增强重建功能的周期性旋转重叠平行线)和涡轮螺旋桨技术提供了一种校正运动伪影的有效方法。通过将这些技术结合在一起,我们证明了新的TP-IDEAL方法能够在进行稳健的运动校正的同时提供可靠的水脂分离。对涡轮螺旋桨序列进行了修改以获取源图像,并调整了运动校正算法以确保不同回波图像之间的配准。进行了理论计算以预测梯度回波的最佳偏移和间距。采集了体模图像,并将结果与常规FSE-IDEAL进行了比较。使用人脑的T1加权和T2加权图像来证明运动校正的有效性。还采集了骨盆、膝盖和足部的TP-IDEAL图像,显示了该技术在一般临床应用中的巨大潜力。