Wu Hochong H, Lee Jin Hyung, Nishimura Dwight G
Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, California 94305-9510, USA.
Magn Reson Med. 2009 Mar;61(3):639-49. doi: 10.1002/mrm.21865.
The concentric rings two-dimensional (2D) k-space trajectory enables flexible trade-offs between image contrast, signal-to-noise ratio (SNR), spatial resolution, and scan time. However, to realize these benefits for in vivo imaging applications, a robust method is desired to deal with fat signal in the acquired data. Multipoint Dixon techniques have been shown to achieve uniform fat suppression with high SNR-efficiency for Cartesian imaging, but application of these methods for non-Cartesian imaging is complicated by the fact that fat off-resonance creates significant blurring artifacts in the reconstruction. In this work, two fat-water separation algorithms are developed for the concentric rings. A retracing design is used to sample rings near the center of k-space through multiple revolutions to characterize the fat-water phase evolution difference at multiple time points. This acquisition design is first used for multipoint Dixon reconstruction, and then extended to a spectroscopic approach to account for the trajectory's full evolution through 3D k-t space. As the trajectory is resolved in time, off-resonance effects cause shifts in frequency instead of spatial blurring in 2D k-space. The spectral information can be used to assess field variation and perform robust fat-water separation. In vivo experimental results demonstrate the effectiveness of both algorithms.
同心环二维(2D)k空间轨迹能够在图像对比度、信噪比(SNR)、空间分辨率和扫描时间之间实现灵活权衡。然而,为了在体内成像应用中实现这些优势,需要一种稳健的方法来处理采集数据中的脂肪信号。多点狄克逊技术已被证明在笛卡尔成像中能够以高SNR效率实现均匀的脂肪抑制,但将这些方法应用于非笛卡尔成像时,由于脂肪失谐在重建中会产生显著的模糊伪影,因此变得复杂。在这项工作中,针对同心环开发了两种脂肪-水分离算法。采用回溯设计通过多次旋转对k空间中心附近的环进行采样,以在多个时间点表征脂肪-水相演变差异。这种采集设计首先用于多点狄克逊重建,然后扩展到一种光谱方法,以考虑轨迹在3D k-t空间中的完整演变。由于轨迹在时间上得到解析,失谐效应会导致频率偏移,而不是在2D k空间中产生空间模糊。光谱信息可用于评估场变化并进行稳健的脂肪-水分离。体内实验结果证明了这两种算法的有效性。