Kondo Takeshi
Division of Pathology (Molecular Pathology), Kobe University Graduate School of Medicine, Japan.
Pol J Pathol. 2008;59(3):183-5.
Invasive micropapillary carcinoma (IMPC) is defined as a carcinoma composed of small clusters of tumor cells lying within clear spaces which simulate lymphovascular channels. This histologic pattern has been described in various organs, including the breast, lung, urinary bladder, ovary, stomach, pancreas, and major salivary glands. Although rarely observed as a pure histologic component, IMPC is usually mixed with conventional carcinoma, and is therefore often referred to as carcinoma with a micropapillary component. IMPCs are invariably associated with a high degree of aggressiveness, extensive lymphovascular invasion, extensive lymph node metastases, and poor prognosis. I herein describe a case of primary IMPC originating in colon polyp as a minor histologic component.
浸润性微乳头状癌（IMPC）被定义为一种由位于类似淋巴管腔的透明间隙内的小簇肿瘤细胞组成的癌。这种组织学模式已在包括乳腺、肺、膀胱、卵巢、胃、胰腺和大唾液腺在内的各种器官中被描述。尽管很少作为一种纯粹的组织学成分被观察到，但IMPC通常与传统癌混合，因此常被称为具有微乳头成分的癌。IMPC总是与高度侵袭性、广泛的淋巴管侵犯、广泛的淋巴结转移和不良预后相关。在此，我描述一例起源于结肠息肉且作为次要组织学成分的原发性IMPC病例。
