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[慢性亚硝酸盐中毒孕鼠及其胎儿体内的自由基过程与红细胞系]

[Free radical processes and erythron in pregnant rats and their fetuses in chronic nitrite intoxication].

作者信息

Ivanova A S, Sitnikova O G, Nazarov S B

出版信息

Gig Sanit. 2008 Jul-Aug(4):72-5.

Abstract

The purpose of the investigation was to study changes in the intensity of induced chemiluminescence of serum and erythrocytes, as well as the erythrocytic system in pregnant rats and fetuses in chronic nitrite intoxication. In nitrite-intoxicated pregnant rats, the level of erythropenia was less than that in intact pregnant rats, fetuses being observed to have stimulated erythropoiesis. In intact pregnant animals, the intensity of induced chemiluminescence on day 20 was higher than the baseline and throughout the follow-up in nitrite-intoxicated adult animals and fetuses.

摘要

本研究的目的是研究慢性亚硝酸盐中毒的妊娠大鼠及其胎儿血清和红细胞诱导化学发光强度的变化,以及红细胞系统的变化。在亚硝酸盐中毒的妊娠大鼠中,红细胞减少水平低于未中毒的妊娠大鼠,观察到胎儿的红细胞生成受到刺激。在未中毒的妊娠动物中,第20天诱导化学发光强度高于基线水平,且在亚硝酸盐中毒的成年动物和胎儿的整个随访过程中均如此。

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