Kiziltan M E, Benbir G
Istanbul University Cerrahpasa, Faculty of Medicine, Department of Neurology, Istanbul, Turkey.
Electromyogr Clin Neurophysiol. 2008 Nov-Dec;48(8):351-7.
Diabetic polyneuropathy (PNP) is an important risk factor for foot ulcers. Diabetic dermopathy is more frequent in patients with diabetic neuropathy. We compared clinical and electrophysiological characteristics of PNP localizations/recurrences of foot ulcers, and diabetic dermopathy (DD) between sexes.
Eighty-eight diabetic patients (44 men, 44 women) had an evaluation regarding detailed history of their diseases, lesion-related data, and clinical examination. Nerve conduction velocities (NCV), compound motor action potentials (CMAP), distal latencies (DL), and sensory nerve action potentials were assessed from the right and left peroneal, right median/ulnar nerves.
The presence of DD was more common in men (p < 0.001). The mean NCV of ulnar nerves was slower (p < 0.001); mean CMAP values were lower (p = 0.006); and mean DL was longer in men with compared to women (p = 0.003). Although EMG features of peroneal nerves showed no significant difference, diabetic men had more common and severe peroneal nerve involvement (p = 0.004). Carpal tunnel syndrome was more common in women, though not significant. Patients with right-sided ulcers had lower CMAP amplitudes on the right peroneal nerves in regard to left peroneal nerves (p = 0.009).
Our findings suggest that ulnar nerves are more commonly involved in men, with lower CMAP slower NCV values, and longer DL values.
糖尿病性多发性神经病（PNP）是足部溃疡的重要危险因素。糖尿病性皮肤病在糖尿病性神经病患者中更为常见。我们比较了男女之间足部溃疡的PNP定位/复发以及糖尿病性皮肤病（DD）的临床和电生理特征。
88例糖尿病患者（44例男性，44例女性）接受了关于其疾病详细病史、病变相关数据和临床检查的评估。从左右腓总神经、右正中/尺神经评估神经传导速度（NCV）、复合运动动作电位（CMAP）、远端潜伏期（DL）和感觉神经动作电位。
DD在男性中更为常见（p < 0.001）。男性尺神经的平均NCV较慢（p < 0.001）；平均CMAP值较低（p = 0.006）；与女性相比，男性的平均DL更长（p = 0.003）。虽然腓总神经的肌电图特征无显著差异，但糖尿病男性腓总神经受累更常见且更严重（p = 0.004）。腕管综合征在女性中更常见，尽管不显著。右侧溃疡患者右侧腓总神经的CMAP振幅相对于左侧腓总神经较低（p = 0.009）。
我们的研究结果表明，男性尺神经受累更为常见，CMAP值较低，NCV较慢，DL值较长。
