Davis G L, Spector G J, Strauss M, Middlekamp J N
Arch Pathol Lab Med. 1977 Mar;101(3):118-21.
A premature male infant, who died 22 days after birth with hyaline membrane disease, was found to have had cytomegalic inclusion disease at autopsy. Histopathologic examination of the temporal bones showed cytomegalovirus (CMV) infection of the entire endolabyrinth without involvement of the neural and sensory structures. These findings support the thesis that late gestational or perinatal fetal CMV infection results in an endolymphatic labyrinthitis. We hypothesize that blood-borne virus passes from the stria vascularis into the endolymphatic spaces and infects the nonneurosensory epithelium. This pattern of infection differs from the perilabyrinthitis of human varicellazoster and experimentally produced mouse CMV.
一名早产男婴出生22天后死于透明膜病，尸检发现患有巨细胞包涵体病。颞骨的组织病理学检查显示整个内迷路有巨细胞病毒（CMV）感染，而神经和感觉结构未受累。这些发现支持了这样的论点，即妊娠晚期或围产期胎儿CMV感染会导致内淋巴迷路炎。我们推测血行病毒从血管纹进入内淋巴间隙并感染非神经感觉上皮。这种感染模式不同于人类水痘带状疱疹和实验性产生的小鼠CMV的迷路周围炎。
