Int J Cardiol. 2010 Jul 23;142(3):298-300. doi: 10.1016/j.ijcard.2008.11.118. Epub 2008 Dec 20.
In patients with congestive heart failure (CHF) cachexia as well as Cheyne-Stokes respiration (CSR) are well known disorders. The relationship between CSR and cardiac cachexia however, remains unclear so far. Clinical as well as full-night polysomnographic data from 12 cachectic patients were compared to 13 non-cachectic patients with CHF. The non-cachectic patients did not differ significantly in age (57.3+/-11.6 vs 64.8+/-14.5 years), body mass index (26.4+/-4.0 vs 25.2+/-3.2 kg m-(2)) or ejection fraction (21.8+/-5 vs 23.3+/-7%) from cachectic patients. The weight loss was 2.1+/-2.3 kg in non-cachectic vs 11.5+/-2.7 kg in cachectic patients (p<0.0001). A significant difference was detected for the prevalence CSR (5 vs 10 patients, p<0.03). In this study a high prevalence of sleep breathing disorders, in particular of CSR in CHF patients with cachexia was detected.
充血性心力衰竭（CHF）患者常伴有恶病质和 Cheyne-Stokes 呼吸（CSR），CSR 与心脏恶病质之间的关系尚不清楚。本研究对比了 12 例恶病质 CHF 患者和 13 例非恶病质 CHF 患者的临床和整夜多导睡眠图数据。非恶病质组患者在年龄（57.3+/-11.6 岁 vs 64.8+/-14.5 岁）、体重指数（26.4+/-4.0 千克/米(2) vs 25.2+/-3.2 千克/米(2))或射血分数（21.8+/-5% vs 23.3+/-7%）方面与恶病质组患者无显著差异。非恶病质组患者体重减轻 2.1+/-2.3 千克，恶病质组体重减轻 11.5+/-2.7 千克（p<0.0001）。CSR 的患病率有显著差异（5 例 vs 10 例，p<0.03）。本研究发现，CHF 恶病质患者睡眠呼吸障碍，尤其是 CSR 的患病率较高。
