Vascular Surgery Department, Norfolk and Norwich University Hospital NHS Trust, Norwich, United Kingdom.
Angiology. 2009;60(6):732-8. doi: 10.1177/0003319708329335. Epub 2008 Dec 18.
The aim of this study was to assess the relationship between ankle brachial pressure index and pulse wave velocity in patients with peripheral arterial disease.
Brachial-knee and brachial-ankle pulse wave velocity were measured by pneumoplethysmography using cuffs in a standard technique. Correlation between pulse wave velocity and Doppler-ankle brachial pressure index was assessed by Spearman correlation and receiver operating curves.
A total of 133 claudicants were assessed. Analysis by developing receiver operating curves for ankle brachial pressure index and pulse wave velocity showed that patients with ankle brachial pressure index over 0.6 were more likely to have a bk-pulse wave velocity over 9.2 m/s and ba-pulse wave velocity over 9.5 m/s.
These results show for the first time that nondiabetic vascular patients may have measurable significant arterial stiffness independent of an impaired ankle brachial pressure index. These data suggest that pulse wave velocity may be valuable in screening and evaluating the severity of peripheral arterial disease.
本研究旨在评估周围动脉疾病患者的踝臂血压指数与脉搏波速度之间的关系。
采用肱-膝和肱-踝脉搏波速度测量法，通过压力袖带以标准技术进行测量。通过 Spearman 相关分析和受试者工作特征曲线评估脉搏波速度与多普勒踝臂血压指数之间的相关性。
共评估了 133 名跛行患者。通过为踝臂血压指数和脉搏波速度制定受试者工作特征曲线进行分析，结果表明，踝臂血压指数超过 0.6 的患者更有可能出现 bk-脉搏波速度超过 9.2m/s 和 ba-脉搏波速度超过 9.5m/s。
这些结果首次表明，非糖尿病血管患者可能存在可测量的显著动脉僵硬度，而踝臂血压指数不受影响。这些数据表明，脉搏波速度可能有助于筛查和评估周围动脉疾病的严重程度。
