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血小板浓缩物的特性,尤其涉及血细胞单采术C血小板细胞:平均血小板体积(dMPV)与其他血小板功能检测之间的相关性

Characteristics of platelet concentrates, with particular reference to Autopheresis C Plateletcell: correlation between dMPV and other tests for platelet function.

作者信息

Vickers M V, Ip A H, Cutts M, Tandy N P, Seghatchian M J

机构信息

North London Blood Transfusion Centre, Colindale, UK.

出版信息

Blood Coagul Fibrinolysis. 1991 Apr;2(2):361-6.

PMID:1909905
Abstract

The quality of platelet concentrates (PC) collected by the Autopheresis C cell separator was assessed in two Regional Transfusion Centres taking part in a multicentre study. This study also enabled the assessment of a new simple, rapid test of platelet function and comparison with more established tests, such as aggregation to adenosine diphosphate, as a tool for the quality testing of PC. The new test, based upon the measurement of mean platelet volume using automated haematological cell analysers, is rapid and uses the same samples as those used to estimate the platelet and leucocyte content of the concentrates. The high correlation between this test and the other tests of platelet function used in the study suggests that it is an ideal tool in the quality testing of platelet concentrates.

摘要

在参与一项多中心研究的两个地区输血中心,对通过血细胞分离机C采集的血小板浓缩物(PC)的质量进行了评估。该研究还能够对一种新的简单、快速的血小板功能检测方法进行评估,并与更成熟的检测方法(如对二磷酸腺苷的聚集反应)进行比较,以此作为血小板浓缩物质量检测的工具。这项基于使用自动血液学细胞分析仪测量平均血小板体积的新检测方法快速,且使用与用于估计浓缩物中血小板和白细胞含量相同的样本。该检测方法与研究中使用的其他血小板功能检测方法之间的高度相关性表明,它是血小板浓缩物质量检测的理想工具。

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