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[淋巴结清扫术在阴茎癌治疗中的意义]

[The significance of lymphadenectomy in the management of penile cancer].

作者信息

Angerer-Shpilenya M, Jakse G

机构信息

Urologische Klinik, Universitätsklinikum, RWTH-Aachen, Pauwelsstr. 30, 50072 Aachen.

出版信息

Urologe A. 2009 Jan;48(1):54-8. doi: 10.1007/s00120-008-1761-y.

DOI:10.1007/s00120-008-1761-y
PMID:19099283
Abstract

Inguinal lymphadenectomy is performed according to the clinical features as well as the risk factors of the primary tumor. In cases involving more than two positive lymph nodes or extranodal growth as well as positive imaging, pelvic lymphadenectomy is indicated. Large or fixed inguinal nodes as well as iliac lymph nodes seen on computed tomography scanning are a good indication for neoadjuvant rather than adjuvant chemotherapy.

摘要

腹股沟淋巴结清扫术根据原发肿瘤的临床特征以及危险因素进行。对于涉及两个以上阳性淋巴结或结外生长以及影像学检查呈阳性的病例,建议进行盆腔淋巴结清扫术。计算机断层扫描显示的大的或固定的腹股沟淋巴结以及髂淋巴结是新辅助化疗而非辅助化疗的良好指征。

相似文献

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[The significance of lymphadenectomy in the management of penile cancer].[淋巴结清扫术在阴茎癌治疗中的意义]
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本文引用的文献

1
Taxanes in combination with cisplatin and fluorouracil for advanced penile cancer: preliminary results.紫杉烷联合顺铂和氟尿嘧啶治疗晚期阴茎癌:初步结果
Eur Urol. 2009 Mar;55(3):546-51. doi: 10.1016/j.eururo.2008.07.014. Epub 2008 Jul 14.
2
Lymph-node metastases in intermediate-risk squamous cell carcinoma of the penis.阴茎中危鳞状细胞癌的淋巴结转移
BJU Int. 2008 Nov;102(9):1102-6. doi: 10.1111/j.1464-410X.2008.07744.x. Epub 2008 May 16.
3
Histologic grade and perineural invasion are more important than tumor thickness as predictor of nodal metastasis in penile squamous cell carcinoma invading 5 to 10 mm.
在浸润深度为5至10毫米的阴茎鳞状细胞癌中,组织学分级和神经周围浸润作为淋巴结转移的预测指标比肿瘤厚度更为重要。
Am J Surg Pathol. 2008 Jul;32(7):974-9. doi: 10.1097/PAS.0b013e3181641365.
4
Evaluation of dynamic sentinel lymph node biopsy in patients with squamous cell carcinoma of the penis and palpable inguinal nodes.阴茎鳞状细胞癌伴可触及腹股沟淋巴结患者的动态前哨淋巴结活检评估
BJU Int. 2008 Aug;102(3):305-9. doi: 10.1111/j.1464-410X.2008.07628.x. Epub 2008 Apr 11.
5
How accurately do Solsona and European Association of Urology risk groups predict for risk of lymph node metastases in patients with squamous cell carcinoma of the penis?索尔索纳(Solsona)和欧洲泌尿外科学会风险分组对阴茎鳞状细胞癌患者淋巴结转移风险的预测准确性如何?
Urology. 2008 Feb;71(2):328-33. doi: 10.1016/j.urology.2007.09.055.
6
Predicting pelvic lymph node metastases in penile cancer patients: a comparison of computed tomography, Cloquet's node, and disease burden of inguinal lymph nodes.预测阴茎癌患者盆腔淋巴结转移:计算机断层扫描、闭孔淋巴结及腹股沟淋巴结疾病负担的比较
Onkologie. 2008 Feb;31(1-2):37-41. doi: 10.1159/000112462. Epub 2008 Jan 22.
7
Radical excision of the inguinal and iliac lymph glands; a study based upon 450 anatomical dissections and upon supportive clinical observations.腹股沟和髂淋巴结根治性切除术:基于450例解剖 dissections 及支持性临床观察的研究。 (这里“dissections”直译为“解剖”,结合语境可能是“解剖研究”之类更准确的表达,但按照要求未添加解释,保留原文形式)
Surg Gynecol Obstet. 1948 Dec;87(6):679-94.
8
Squamous cell carcinoma antigen correlates with tumor burden but lacks prognostic potential for occult lymph node metastases in penile cancer.鳞状细胞癌抗原与肿瘤负荷相关,但对阴茎癌隐匿性淋巴结转移缺乏预后评估价值。
Urology. 2007 Nov;70(5):975-9. doi: 10.1016/j.urology.2007.07.013.
9
Evaluation of dynamic lymphoscintigraphy and sentinel lymph-node biopsy for detecting occult metastases in patients with penile squamous cell carcinoma.动态淋巴闪烁造影术和前哨淋巴结活检在检测阴茎鳞状细胞癌患者隐匿性转移中的应用评估
BJU Int. 2007 Sep;100(3):561-5. doi: 10.1111/j.1464-410X.2007.07013.x. Epub 2007 Jun 18.
10
The prognostic significance of p53, Ki-67, epithelial cadherin and matrix metalloproteinase-9 in penile squamous cell carcinoma treated with surgery.p53、Ki-67、上皮钙黏蛋白和基质金属蛋白酶-9在手术治疗阴茎鳞状细胞癌中的预后意义
BJU Int. 2007 Jul;100(1):204-8. doi: 10.1111/j.1464-410X.2007.06908.x. Epub 2007 Apr 13.