Naumann Carsten M, Alkatout Ibrahim, Al-Najar Amr, Korda Joanna Beate, Hegele Axel, Bolenz Christian, Ziegler Heiko, Klöppel Günter, Juenemann Klaus-Peter, van der Horst Christof
Department of Urology and Paediatric Urology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany.
BJU Int. 2008 Nov;102(9):1102-6. doi: 10.1111/j.1464-410X.2008.07744.x. Epub 2008 May 16.
To evaluate the metastatic risk of pT1 G2 squamous cell carcinoma (SCC) of the penis.
We retrospectively reviewed 20 patients with pT1 G2 penile SCC and determined their groin status at first presentation, their nodal status after inguinal lymph node dissection and their follow-up for at least 18 months.
Four of the 20 patients had a clinically positive groin; three of these were found to have lymph node metastases. Among the 16 patients with a clinically negative groin, one of five who had surgical lymph node staging had lymph node metastases. During surveillance six of 11 patients developed lymph node metastases. There was lymphovascular invasion in three of 10 patients with lymph node metastases.
As the metastatic risk of pT1 G2 penile SCC was 50% in this series of patients, and 44% in those with an initially negative groin, surgical staging of inguinal lymph nodes is recommended in patients with pT1 G2 penile SCC.
评估阴茎pT1 G2鳞状细胞癌（SCC）的转移风险。
我们回顾性分析了20例阴茎pT1 G2 SCC患者，确定其初次就诊时的腹股沟状态、腹股沟淋巴结清扫术后的淋巴结状态以及至少18个月的随访情况。
20例患者中有4例腹股沟临床检查呈阳性；其中3例发现有淋巴结转移。在16例腹股沟临床检查呈阴性的患者中，5例接受手术淋巴结分期的患者中有1例发生淋巴结转移。在随访期间，11例患者中有6例出现淋巴结转移。10例有淋巴结转移的患者中有3例存在淋巴管浸润。
在这组患者中，阴茎pT1 G2 SCC的转移风险为50%，最初腹股沟阴性的患者转移风险为44%，因此建议对阴茎pT1 G2 SCC患者进行腹股沟淋巴结手术分期。
