Lu Y, Wu L Q, Zhang B Y, Cao J Y
Department of Hepatobiliary Surgery, Affiliated Hospital of Medical College, Qingdao University, Qingdao, People's Republic of China.
Transplant Proc. 2008 Dec;40(10):3784-6. doi: 10.1016/j.transproceed.2008.03.164.
Graft-versus-host disease (GVHD) is a rare, serious complication after liver transplantation. The incidence is about 1% abroad, but because of difficulties in diagnosis and treatment, the mortality rate is high (80%). Up to now, 78 patients have been reported to have this complication after liver transplantation worldwide; despite various therapeutic programs, the mortality of GVHD after orthotopic liver transplantation (OLT) is still high. Herein we have reported successful treatment of a case of GVHD after liver transplantation.
移植物抗宿主病(GVHD)是肝移植后一种罕见的严重并发症。国外发病率约为1%,但由于诊断和治疗困难,死亡率很高(80%)。截至目前,全球范围内已有78例肝移植后出现这种并发症的报道;尽管有各种治疗方案,原位肝移植(OLT)后GVHD的死亡率仍然很高。在此,我们报告了1例肝移植后GVHD的成功治疗病例。