Bazmamoun Hassan, Ghorbanpour Manoochehr, Mousavi-Bahar Seyed Habibollah
Department of Pediatrics, Division of Gastroenterology, School Of Medicine, Hamadan University Of Medical Sciences, Hamadan, Iran.
Urol J. 2008 Fall;5(4):233-6.
Circumcision is one of the most common surgical operations throughout the world, and meatal stenosis is one its late complications. We evaluated the topical use of a lubricant jelly after circumcision in boys in order to reduce the risk of meatal stenosis.
A randomized control trial was performed, in which 2 groups of boys younger the 2 years old underwent circumcision according to the sleeve method. The parents in the study group were instructed to use petroleum jelly on the circumcision site after each diaper change for 6 months. In the control group, no topical medication was used. The children were followed up regularly and evaluated for meatal stenosis, bleeding, infection, and recovery time.
A total of 197 boys in each group completed the study. None of the children in the study group but 13 (6.6%) in the control group developed meatal stenosis (P < .001). Infection of the circumcision site was seen in 3 (1.5%) and 23 (11.7%) children of the lubricant and control groups, respectively (P < .001), and bleeding was seen in 6 (3.0%) and 37 (18.8%), respectively (P < .001). The mean time of recovery in the lubricant group was 3.8 +/- 1.2 days, while it was 6.9 +/- 4.2 days in the control group (P = .03).
Based on the findings of this study, it seems logical to use a lubricant jelly for reducing postcircumcision meatal stenosis and other complications.
包皮环切术是全球最常见的外科手术之一，尿道口狭窄是其后期并发症之一。我们评估了在男孩包皮环切术后局部使用润滑凝胶以降低尿道口狭窄风险的效果。
进行了一项随机对照试验，两组2岁以下男孩按袖套法接受包皮环切术。研究组的家长被指示在每次更换尿布后在包皮环切部位涂抹凡士林，持续6个月。对照组未使用局部药物。对儿童进行定期随访，并评估尿道口狭窄、出血、感染及恢复时间。
每组共有197名男孩完成研究。研究组无儿童发生尿道口狭窄，而对照组有13名（6.6%）发生尿道口狭窄（P <.001）。润滑凝胶组和对照组分别有3名（1.5%）和23名（11.7%）儿童出现包皮环切部位感染（P <.001），分别有6名（3.0%）和37名（18.8%）儿童出现出血（P <.001）。润滑凝胶组的平均恢复时间为3.8±1.2天，而对照组为6.9±4.2天（P =.03）。
基于本研究结果，使用润滑凝胶来减少包皮环切术后尿道口狭窄及其他并发症似乎是合理的。
