Darling Gail
University of Toronto, Toronto, Ontario, Canada.
J Surg Oncol. 2009 Mar 15;99(4):189-93. doi: 10.1002/jso.21209.
Lymph node metastases are common in esophageal cancer and are associated with a poor prognosis. Resection and examination of 15-18 lymph nodes is required for adequate staging of esophageal cancer. Improved survival is associated with involvement of five or fewer nodes or lymph node ratio (LNR) of < 0.10-0.20. More extensive lymph node dissection during esophagectomy offers improved staging but may also provide therapeutic benefit in terms of control of locoregional disease and possibly improved overall survival.
淋巴结转移在食管癌中很常见，且与预后不良相关。食管癌进行充分分期需要切除并检查15 - 18个淋巴结。淋巴结转移数目为5个及以下或淋巴结转移率（LNR）< 0.10 - 0.20与生存率提高相关。食管癌切除术中更广泛的淋巴结清扫可改善分期，但在控制局部区域疾病方面也可能具有治疗益处，并可能提高总体生存率。
