te Velde E R, Merkus J M W M, van Leeuwen F E, Verloove-Vanhorick S P, Braat D D M
Voortplantingsgeneeskunde, Utrecht.
Ned Tijdschr Geneeskd. 2008 Nov 29;152(48):2592-5.
In a recent article in this journal it was stated that Dutch women were sensible in having their first child between the ages of 25 and 35 years. One of the conclusions was that associated health risks increase after the age of 35 but are still acceptable even at the age of 40. We demonstrate that these conclusions were based on flawed assumptions. Postponing pregnancy until after the age of 30 increases the risks of infertility and breast cancer. Motherhood at a later age is associated with an increase in obstetrical complications, miscarriage and other adverse effects on the child. Therefore, for couples planning a family with 2 children or more, it would be sensible to have the first pregnancy not long after the mother reaches the age of 30 years, or even earlier. Couples should be informed on the risks of late parenthood in order to be able to take the right decisions concerning family planning.
在本期刊最近的一篇文章中指出,荷兰女性在25至35岁之间生育头胎是明智的。其中一个结论是,35岁之后相关健康风险会增加,但即使到40岁这些风险仍可接受。我们证明这些结论是基于有缺陷的假设。将怀孕推迟到30岁之后会增加不孕和患乳腺癌的风险。晚育与产科并发症、流产以及对孩子的其他不良影响增加有关。因此,对于计划生育两个或更多孩子的夫妇来说,在母亲刚过30岁甚至更早的时候就首次怀孕是明智的。应该让夫妇了解晚育的风险,以便他们能够就计划生育做出正确的决定。