Mortell Alan E, Azizkhan Richard G
Division of Pediatric and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
Semin Pediatr Surg. 2009 Feb;18(1):12-9. doi: 10.1053/j.sempedsurg.2008.10.003.
Esophageal atresia/tracheoesophageal fistula (EA/TEF) repair using an open muscle-sparing thoracotomy has been the standard approach used in our institution. Whereas perioperative mortality is now very uncommon, short- and long-term morbidity is very common in these patients. However, the complexity of the esophageal anatomy and significant comorbidities appear to be important contributors to significant complications in these patients. At least 30% of the EA/TEF patients required esophageal dilatations for anastomotic stricture; this increased to 50% for patients with pure EA. Gastroesophageal reflux requiring an antireflux procedure was performed 23% of the time for EA/TEF and 30% for EA patients. In addition, there were a few complications, such as winging of the scapula and scoliosis, that were attributed in part to the utilization of a nonmuscle-sparing thoracotomy. The standard muscle-sparing thoracotomy remains a very versatile and useful approach to repairing esophageal atresia, and it is the standard for repairing more complex anatomical variants. The self-reported long-term quality of life in these patients is very good, except for a few individuals with protracted feeding disorders and severe dysphagia.
在我们机构,采用开放肌肉保留胸廓切开术修复食管闭锁/气管食管瘘(EA/TEF)一直是标准方法。虽然围手术期死亡率现在已非常罕见,但这些患者的短期和长期发病率却很常见。然而,食管解剖结构的复杂性和显著的合并症似乎是这些患者出现严重并发症的重要因素。至少30%的EA/TEF患者因吻合口狭窄需要进行食管扩张;单纯EA患者这一比例增至50%。对于EA/TEF患者,23%的情况下需要进行抗反流手术来处理胃食管反流,而EA患者这一比例为30%。此外,还出现了一些并发症,如肩胛骨翼状畸形和脊柱侧弯,部分原因是采用了非肌肉保留胸廓切开术。标准的肌肉保留胸廓切开术仍然是修复食管闭锁非常通用且有用的方法,也是修复更复杂解剖变异的标准方法。除了少数有长期喂养障碍和严重吞咽困难的个体外,这些患者自我报告的长期生活质量非常好。