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[普罗帕酮对心房颤动和心房扑动患者的致心律失常作用]

[Proarrhythmic effect of propafenone in patients with atrial fibrillation and atrial flutter].

作者信息

Jastrzebski Marek

机构信息

I Klinika Kardiologii i Nadciśnienia Tetniczego, ul. Kopernika 17, 31-501 Kraków.

出版信息

Kardiol Pol. 2008 Nov;66(11):1221-4; discussion 1225.

PMID:19105102
Abstract

We present two cases of proarrhythmia after propafenone treatment. In the first case slowing of the flutter cycle length from 205 ms to 290 ms resulted in a change from well tolerated two to one atrioventricular conduction to one to one conduction with hypotension and presyncope. In the second case organization of atrial fibrillation to atypical atrial flutter and use-dependent left bundle branch block resulted in fast broad QRS tachycardia that mimicked ventricular tachycardia.

摘要

我们报告两例普罗帕酮治疗后发生的心律失常。第一例中,扑动周期长度从205毫秒减慢至290毫秒,导致房室传导从可耐受的2:1变为1:1传导,并伴有低血压和晕厥前期。第二例中,房颤转变为非典型房扑以及使用依赖性左束支传导阻滞导致快速宽QRS心动过速,酷似室性心动过速。

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