[脐部转移瘤一例（玛丽·约瑟夫修女结节）]

[A case of metastases of umbilicus (Sister Mary Joseph's nodule)].

作者信息

Yamashita Shinya, Sakon Masato, Hiura Yuichiro, Nakano Katsutoshi, Higaki Naozumi, Murakami Masakazu, Hayashida Hirohito, Kan Kazuomi, Ichihara Takao

机构信息

Dept. of Surgery, Nishinomiya Municipal Central Hospital.

出版信息

Gan To Kagaku Ryoho. 2008 Nov;35(12):2112-4.

PMID:19106540

Abstract

We report a case of advanced unresectable pancreatic cancer (cT4N1M0/stage IVa). The patient was a 68-year-old man. Chemo-radiation therapy (CRT) with GEM (1,000 mg/body) was administered once a week on days 1, 8 and 15 for 3 weeks. The radiotherapy dose was 45 Gy (1.5 Gy x 2/day, 15 days). After CRT, the patient was treated with a GEM+ UFT-E combination chemotherapy. When that was done, CT scan revealed metastases of umbilicus (Sister Mary Joseph's nodule) and the liver. Microwave Coagulation Therapy for the liver metastasis and tumorectomy for metastasis of umbilicus were performed. But he died after 4 months from the therapies.

摘要

我们报告一例晚期不可切除胰腺癌（cT4N1M0/IVa期）。患者为一名68岁男性。采用吉西他滨（1000mg/体）进行化疗放疗（CRT），每周一次，于第1、8和15天给药，共3周。放疗剂量为45Gy（1.5Gy×2/天，共15天）。CRT后，患者接受吉西他滨+优福定联合化疗。完成该治疗后，CT扫描显示脐部（玛丽·约瑟夫修女结节）和肝脏转移。对肝转移灶进行了微波凝固治疗，对脐部转移灶进行了肿瘤切除术。但他在治疗后4个月死亡。