Colla Themis Getsos, Lovatto Louise, Duquia Rodrigo Pereira
Santa Casa de Porto Alegre, Porto Alegre, RS, Brazil.
An Bras Dermatol. 2009 Jul;84(3):297-8. doi: 10.1590/s0365-05962009000300015.
A 56-year-old man was hospitalized with a history of diffuse abdominal pain. Cutaneous examination revealed an erythematous to violaceous, infiltrative nodule of the umbilicus. Histologic examination demonstrated poorly differentiated adenocarcinoma. Abdominal tomography showed advanced pancreatic cancer with metastatic involvement of the liver and the diagnosis of pancreatic adenocarcinoma with umbilical metastasis -- Sister Mary Joseph's nodule.
一名56岁男性因弥漫性腹痛病史入院。皮肤检查发现脐部有一个从红斑到紫蓝色的浸润性结节。组织学检查显示为低分化腺癌。腹部断层扫描显示晚期胰腺癌伴肝转移,诊断为胰腺腺癌伴脐部转移——玛丽·约瑟夫修女结节。