Xue Xiaonan, Hoover Donald R
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Methods Mol Biol. 2009;471:239-72. doi: 10.1007/978-1-59745-416-2_13.
In this chapter, we discuss statistical methods for various study designs that are commonly used in epidemiological research and particularly in cancer epidemiological research. After a brief review of basic concepts in epidemiological studies, statistical methods for case-control studies and cohort studies are discussed. Statistical methods for nested case-control and case-cohort studies, which have been increasingly used in cancer epidemiology, also are discussed. This chapter is designed for cancer epidemiologists who understand basic statistical methods for commonly used epidemiological study designs and are able to initiate power and sample size calculations. Therefore, this chapter emphasizes newly developed statistical methods for epidemiological studies as well as study planning.
在本章中，我们将讨论各种常用于流行病学研究，特别是癌症流行病学研究的不同研究设计的统计方法。在简要回顾流行病学研究的基本概念之后，我们将讨论病例对照研究和队列研究的统计方法。还将讨论在癌症流行病学中越来越常用的巢式病例对照研究和病例队列研究的统计方法。本章是为那些了解常用流行病学研究设计的基本统计方法并能够进行效能和样本量计算的癌症流行病学家而编写的。因此，本章重点介绍流行病学研究新开发的统计方法以及研究规划。
