Dwyer Daniel J, Kohanski Michael A, Collins James J
Howard Hughes Medical Institute, Center for BioDynamics, Center for Advanced Biotechnology, Boston University, Boston, MA 02215, USA.
Cell. 2008 Dec 26;135(7):1153-6. doi: 10.1016/j.cell.2008.12.016.
In this post-genomic era, our capacity to explore biological networks and predict network architectures has been greatly expanded, accelerating interest in systems biology. Here, we highlight recent systems biology studies in prokaryotes, consider the challenges ahead, and suggest opportunities for future studies in bacterial models.
在这个后基因组时代,我们探索生物网络和预测网络架构的能力得到了极大扩展,这加速了人们对系统生物学的兴趣。在此,我们重点介绍原核生物中近期的系统生物学研究,探讨面临的挑战,并提出在细菌模型中开展未来研究的机会。