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本文引用的文献
1
Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily.
Nat Chem Biol. 2008 Dec;4(12):758-65. doi: 10.1038/nchembio.121. Epub 2008 Oct 26.
2
ThiC is an [Fe-S] cluster protein that requires AdoMet to generate the 4-amino-5-hydroxymethyl-2-methylpyrimidine moiety in thiamin synthesis.
Biochemistry. 2008 Sep 2;47(35):9054-6. doi: 10.1021/bi8010253. Epub 2008 Aug 8.
3
The Radical SAM Superfamily.
Crit Rev Biochem Mol Biol. 2008 Jan-Feb;43(1):63-88. doi: 10.1080/10409230701829169.
4
S-adenosylmethionine as an oxidant: the radical SAM superfamily.
Trends Biochem Sci. 2007 Mar;32(3):101-10. doi: 10.1016/j.tibs.2007.01.002. Epub 2007 Feb 8.
5
A connection between iron-sulfur cluster metabolism and the biosynthesis of 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate in Salmonella enterica.
Microbiology (Reading). 2006 Aug;152(Pt 8):2345-2353. doi: 10.1099/mic.0.28926-0.
6
New glycyl radical enzymes catalysing key metabolic steps in anaerobic bacteria.
Biol Chem. 2005 Oct;386(10):981-8. doi: 10.1515/BC.2005.114.
7
X-ray structure of pyruvate formate-lyase in complex with pyruvate and CoA. How the enzyme uses the Cys-418 thiyl radical for pyruvate cleavage.
J Biol Chem. 2002 Oct 18;277(42):40036-42. doi: 10.1074/jbc.M205821200. Epub 2002 Aug 5.
8
Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods.
Nucleic Acids Res. 2001 Mar 1;29(5):1097-106. doi: 10.1093/nar/29.5.1097.
9
Affinity cleavage at the divalent metal site of porcine NAD-specific isocitrate dehydrogenase.
Protein Sci. 2000 Jan;9(1):104-11. doi: 10.1110/ps.9.1.104.
10
Effects of structure on alpha C-H bond enthalpies of amino acid residues: relevance to H transfers in enzyme mechanisms and in protein oxidation.
Biochemistry. 1999 Jul 13;38(28):9089-96. doi: 10.1021/bi990249x.
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