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医院环境下鼻咽癌的人口统计学研究。

Demographic study of nasopharyngeal carcinoma in a hospital setting.

作者信息

Muchiri M

出版信息

East Afr Med J. 2008 Aug;85(8):406-11. doi: 10.4314/eamj.v85i8.9658.

Abstract

OBJECTIVES

To highlight demographic pattern of nasopharyngeal carcinoma and determine mode and stage of presentation.

DESIGN

Prospective analytical study.

SETTING

Kenyatta National Hospital (KNH)/University of Nairobi, Kenya.

SUBJECTS

One hundred and twenty five patients seen at the ENT department of KNH. These were either referred from other peripheral hospitals or first seen at KNH and satisfied the inclusion criteria. Patients with open neck biopsy were excluded (among other criteria).

RESULTS

Age range of the patients was 13-85 years. Male: Female ratio was 2.2:1 with the highest frequency in the 31-40 years. Most patients presented in late disease (stages III and IV) which carry a poor prognosis. Majority of the patients had neck swelling as the first symptom followed by nose blockage. Several patients referred from peripheral major hospitals and open neck biopsy. Majority of the patients seen were from poor social-economic background.

CONCLUSION

Nasopharyngeal carcinoma is a common malignancy at KNH. Diagnosis is usually made in late stages of the disease when prognosis after full treatment is poor. There is need to make early diagnosis by heightening the index of suspicion among health professionals and probably health education in the community on the need to seek treatment for persistent neck masses.

摘要

目的

突出鼻咽癌的人口统计学模式,并确定其表现方式和分期。

设计

前瞻性分析研究。

地点

肯尼亚内罗毕大学肯雅塔国家医院(KNH)。

研究对象

在KNH耳鼻喉科就诊的125例患者。这些患者要么是从其他周边医院转诊而来,要么是首次在KNH就诊且符合纳入标准。排除了颈部开放性活检的患者(以及其他标准)。

结果

患者年龄范围为13至85岁。男女比例为2.2:1,31至40岁年龄段发病率最高。大多数患者就诊时已处于疾病晚期(III期和IV期),预后较差。大多数患者首发症状为颈部肿胀,其次是鼻塞。有几位患者是从周边大型医院转诊而来且接受了颈部开放性活检。就诊的大多数患者来自社会经济背景较差的群体。

结论

鼻咽癌在KNH是一种常见的恶性肿瘤。通常在疾病晚期才能确诊,此时进行全面治疗后的预后较差。有必要通过提高卫生专业人员的怀疑指数,并可能在社区开展关于持续颈部肿块需寻求治疗的健康教育,来实现早期诊断。

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