Pua K C, Khoo A S B, Yap Y Y, Subramaniam S K, Ong C A, Gopala Krishnan G, Shahid H
Department of Otorhinolaryngology, Hospital Pulau Pinang, Jalan Residensi, 10990 Penang, Malaysia.
Med J Malaysia. 2008 Sep;63 Suppl C:59-62.
Nasopharyngeal carcinoma (NPC) is a cancer which is common in Asia. We report the establishment and early results of a multi-institutional prospective study of nasopharyngeal carcinoma, which seeks to systematically collect data as well as blood and tumour tissue samples from patients diagnosed with nasopharyngeal cancer at six centres in Malaysia. A total of 484 confirmed NPC cases were reported from the six participating centres between 1st July 2007 and 29th February 2008. Of these, 225 were newly diagnosed cases, 53 were recurrent cases and 206 were in remission at the time of reporting. Amongst the newly diagnosed cases, the most common presenting symptom was the presence of neck lumps (42%). Ophthalmo-neurologic symptoms were the presenting symptoms of 11% of the new cases. The majority of cases (75%) presented at stage III/IV.
鼻咽癌（NPC）是一种在亚洲常见的癌症。我们报告了一项鼻咽癌多机构前瞻性研究的建立及早期结果，该研究旨在系统收集马来西亚六个中心诊断为鼻咽癌患者的数据以及血液和肿瘤组织样本。在2007年7月1日至2008年2月29日期间，六个参与中心共报告了484例确诊的鼻咽癌病例。其中，225例为新诊断病例，53例为复发病例，206例在报告时处于缓解期。在新诊断病例中，最常见的症状是颈部肿块（42%）。眼科神经症状是11%新病例的症状。大多数病例（75%）在III/IV期就诊。
