季铵化合物作为玻璃表面抗菌混合涂层的一种新应用。

A novel application of quaternary ammonium compounds as antibacterial hybrid coating on glass surfaces.

作者信息

Saif Muhammad Jawwad, Anwar Jamil, Munawar Munawar Ali

机构信息

Institute of Chemistry, University of the Punjab, New Campus, Lahore 54590, Pakistan.

出版信息

Langmuir. 2009 Jan 6;25(1):377-9. doi: 10.1021/la802878p.

DOI:10.1021/la802878p

PMID:19115872

Abstract

A hybrid coating is prepared on a glass surface by a sol-gel process using tetraethoxysilane (TEOS) and Q(4)N(+)-Si(OR)(3). Transparent coatings with smooth surfaces were investigated against both Gram-positive (Escherichia coli) and Gram-negative bacteria (Staphylococcus aureus). A rapid decrease of the count for both strains was observed within 72 h. A significant correlation has been observed between the concentration of Q(4)N(+)-Si(OR)(S) and the antibacterial activity which has been thoroughly investigated.

摘要

通过溶胶-凝胶法，使用四乙氧基硅烷（TEOS）和Q(4)N(+)-Si(OR)(3)在玻璃表面制备了一种混合涂层。对表面光滑的透明涂层针对革兰氏阳性菌（大肠杆菌）和革兰氏阴性菌（金黄色葡萄球菌）进行了研究。在72小时内观察到两种菌株的数量迅速减少。已对Q(4)N(+)-Si(OR)(S)的浓度与抗菌活性之间的显著相关性进行了深入研究。