Renvoisé A, Raoult D
Unité des rickettsies, CNRS-IRD UMR6236, faculté de médecine, université de la Méditerranée, 27, boulevard Jean-Moulin, 13385 Marseille cedex 5, France.
Med Mal Infect. 2009 Feb;39(2):71-81. doi: 10.1016/j.medmal.2008.11.003. Epub 2008 Dec 31.
Rickettsiae are strictly intracellular bacteria belonging to the Rickettsiaceae family. They are transmitted by various arthropods species, which are either vectors or reservoirs for the bacteria. The specific association between Rickettsieae and the vector are extensively studied, moreover Rickettsieae associated diseases are part of a continuously evolving field. Nevertheless, some rickettsiosis, such as epidemic typhus, have been described since the 16th century. Emerging diseases related to these bacteria are being investigated as well as new species, the implication of which is not always clear in human pathology when they are discovered. Some of these diseases are benign, others may be potentially fatal. Clinicians must therefore be aware of them. These issues are reviewed.
立克次氏体是属于立克次氏体科的严格细胞内细菌。它们通过各种节肢动物传播，这些节肢动物要么是细菌的传播媒介，要么是宿主。立克次氏体与传播媒介之间的特定关联已得到广泛研究，此外，立克次氏体相关疾病是一个不断发展的领域的一部分。然而，一些立克次氏体病，如流行性斑疹伤寒，自16世纪以来就有记载。与这些细菌相关的新出现疾病以及新物种正在被研究，当它们被发现时，其在人类病理学中的影响并不总是清楚的。其中一些疾病是良性的，其他的可能有潜在致命性。因此，临床医生必须对此有所了解。本文对这些问题进行了综述。
