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2002 - 2007年西部兽医学院兽医教学医院犬类尿路病原体的抗菌药物耐药性及流行情况

Antimicrobial resistance and prevalence of canine uropathogens at the Western College of Veterinary Medicine Veterinary Teaching Hospital, 2002-2007.

作者信息

Ball Katherine R, Rubin Joseph E, Chirino-Trejo M, Dowling Patricia M

机构信息

Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.

出版信息

Can Vet J. 2008 Oct;49(10):985-90.

Abstract

Between January 2002 and June 2007, uropathogens were isolated from 473 of 1557 canine urine samples submitted to Prairie Diagnostic Services from the Western College of Veterinary Medicine Veterinary Teaching Hospital. Culture and susceptibility results were analyzed, retrospectively, to estimate the prevalence of common bacterial uropathogens in dogs with urinary tract infections and to identify changes in antimicrobial resistance. The most common pathogens identified were Escherichia coli, Staphylococcus intermedius, Enterococcus spp., and Proteus spp. Antimicrobial resistance increased during the study period, particularly among recurrent E. coli isolates. Using the formula to help select rational antimicrobial therapy (FRAT), bacterial isolates were most likely to be susceptible to gentamicin, fluoroquinolones, amoxicillin-clavulanic acid, and groups 4 and 5 (third generation) cephalosporins.

摘要

在2002年1月至2007年6月期间,从提交给西部兽医学院兽医教学医院草原诊断服务中心的1557份犬类尿液样本中,有473份分离出了尿路病原体。对培养和药敏结果进行了回顾性分析,以估计患有尿路感染的犬类中常见细菌性尿路病原体的流行情况,并确定抗菌药物耐药性的变化。鉴定出的最常见病原体为大肠杆菌、中间葡萄球菌、肠球菌属和变形杆菌属。在研究期间,抗菌药物耐药性有所增加,尤其是在复发性大肠杆菌分离株中。使用帮助选择合理抗菌治疗的公式(FRAT),细菌分离株最有可能对庆大霉素、氟喹诺酮类、阿莫西林-克拉维酸以及4组和5组(第三代)头孢菌素敏感。

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