Delucchi Luis, Fraga Martín, Perelmuter Karen, Cidade Esther, Zunino Pablo
Departamento de Pequeños Animales, Facultad de Veterinaria, Universidad de República, Lasplaces 1550, Montevideo, Uruguay.
Can Vet J. 2008 Oct;49(10):991-4.
The concentrations of lactic acid bacteria (LAB) in 42 vaginal samples from healthy and ill bitches were determined. Eight isolates belonging to the genera Lactobacillus and Enterococcus were selected and identified and their in vitro antimicrobial activity against canine pathogens and their ability to adhere to canine vaginal epithelial cells were determined. There was no correlation between the concentrations of vaginal LAB and clinical status, body temperature, vaginal pH, or age. Although the animals were either well or suffering from various illnesses, LAB were found in almost every sample, and the selected isolates showed promising probiotic-related features. These findings are significant for the design of strategies for the modulation of vaginal microbiota by vaginal LAB isolates.
测定了42份来自健康和患病母犬的阴道样本中乳酸菌(LAB)的浓度。选择并鉴定了8株属于乳酸杆菌属和肠球菌属的分离株,测定了它们对犬类病原体的体外抗菌活性以及它们黏附于犬阴道上皮细胞的能力。阴道LAB浓度与临床状态、体温、阴道pH值或年龄之间没有相关性。尽管这些动物要么健康要么患有各种疾病,但几乎在每个样本中都发现了LAB,并且所选分离株显示出有前景的益生菌相关特性。这些发现对于通过阴道LAB分离株调节阴道微生物群的策略设计具有重要意义。