Vawter Lemuel, Tong Xin, Gemilyan Manik, Yoon Paula W
Division for Heart Disease and Stroke Prevention, Centers for Disease Prevention and Control, Atlanta, GA, USA.
J Clin Hypertens (Greenwich). 2008 Dec;10(12):922-9. doi: 10.1111/j.1751-7176.2008.00049.x.
Antihypertensive agents are one of the most commonly prescribed classes of medications in the country, but patient adherence rates are low. To better understand why rates are low, the authors used data from the 2005 HealthStyles survey and found that among the 1432 respondents who received prescriptions for antihypertensive medications, 407 (28.4%) reported having difficulty taking their medication. "Not remembering'' was the most common reason reported (32.4%), followed by cost (22.6%), having no insurance (22.4%), side effects (12.5%), other reasons (12.3%), not thinking there is any need (9.3%), and having no health care provider (4.7%). In a multivariate model, younger age, lower income, having mental function impairment, and having had a blood pressure check more than 6 months earlier were factors significantly associated with reporting difficulty taking prescribed antihypertensive drugs. Control of hypertension is a significant public health issue, and alleviating barriers to medication adherence should be a major goal toward hypertension management.
抗高血压药物是该国最常用的处方药类别之一,但患者的依从率很低。为了更好地理解依从率低的原因,作者使用了2005年健康生活方式调查的数据,发现在1432名接受抗高血压药物处方的受访者中,407人(占28.4%)报告在服药方面有困难。“忘记服药”是最常报告的原因(占32.4%),其次是费用(占22.6%)、没有保险(占22.4%)、副作用(占12.5%)、其他原因(占12.3%)、认为没有必要服药(占9.3%)以及没有医疗服务提供者(占4.7%)。在一个多变量模型中,年龄较小、收入较低、有心理功能障碍以及在6个多月前进行过血压检查是与报告难以服用规定的抗高血压药物显著相关的因素。高血压的控制是一个重大的公共卫生问题,减轻药物依从性的障碍应该是高血压管理的一个主要目标。