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[1999年至2003年期间我们地区检测到的结核病病例评估]

[Evaluation of tuberculosis cases detected in our region between 1999 and 2003].

作者信息

Ozbay Bülent, Sezgi Cengizhan, Altinöz Orhan, Sertoğullarindan Bünyamin, Tokgöz Necla

机构信息

Department of Chest Diseases, Faculty of Medicine, Yüzüncü Yil University, Van, Turkey.

出版信息

Tuberk Toraks. 2008;56(4):396-404.

Abstract

This study investigates the extent of tuberculosis, its clinical features, the specification of the patients with tuberculosis, and evaluates diagnosis, treatment and their effectiveness in our region. The records of 645 patients admitted to the Tuberculosis Control Dispensary in our between January 1999 and December 2003 were evaluated retrospectively. The incidence of the disease was 0.012% and it was more common among young men and diagnosed mostly by individual examination. Twenty-six percent of the patients had a history of physical contact with a tuberculosis patient. The pulmonary and extra pulmonary involvement of the disease was 51.8% and 48.2%, respectively. Bacteriologic examination of the patients was as follows; 42.2% did not have a bacteriologic examination, 21.7% was smear and culture positive, 26.8% was smear and culture negative, and 8.7% was smear negative and culture positive. Diagnosis of tuberculosis by bacteriologic examination increased from 39.7% to 73.6% within years. Cure rates of the disease were between 12.5% and 34.4%. Completion rates of tuberculosis therapy were between 53.5% and 72.6% and treatment success rates were between 82% and 95% whereas mortality rates varied between 1.7% and 2.8%. In conclusion, we observed that new cases and smear positive cases of tuberculosis were more common among the young and among the people with low socioeconomic status, bacteriologic examination increased over time and the rate of successful treatment was high but the cure rate was low.

摘要

本研究调查了结核病的发病范围、临床特征、结核病患者的具体情况,并评估了本地区结核病的诊断、治疗及其效果。回顾性评估了1999年1月至2003年12月期间在我院结核病防治所住院的645例患者的记录。该病的发病率为0.012%,在青年男性中更为常见,大多通过个体检查确诊。26%的患者有与结核病患者的身体接触史。该疾病的肺部和肺外受累率分别为51.8%和48.2%。患者的细菌学检查结果如下:42.2%未进行细菌学检查,21.7%涂片和培养阳性,26.8%涂片和培养阴性,8.7%涂片阴性和培养阳性。数年内,通过细菌学检查诊断结核病的比例从39.7%增至73.6%。该疾病的治愈率在12.5%至34.4%之间。结核病治疗的完成率在53.5%至72.6%之间,治疗成功率在82%至95%之间,而死亡率在1.7%至2.8%之间。总之,我们观察到结核病新发病例和涂片阳性病例在年轻人和社会经济地位较低的人群中更为常见,细菌学检查随时间增加,治疗成功率高但治愈率低。

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