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哺乳动物运动学习的神经元机制。

Neuronal mechanisms of motor learning in mammals.

作者信息

Asanuma H, Keller A

机构信息

Rockefeller University, New York, NY 10021.

出版信息

Neuroreport. 1991 May;2(5):217-24. doi: 10.1097/00001756-199105000-00001.

DOI:10.1097/00001756-199105000-00001
PMID:1912451
Abstract

Neural mechanisms subserving the acquisition of new motor skills are discussed in this article. Motor learning is defined, in this context, as the acquisition of novel motor skills. It is proposed that complex motor skills are acquired through a process of segmental motor learning, in which movement segments are formed, and retrieved for the execution of the learned skill. Individual movement segments are created by modulating neural activity in loop circuits that link the motor cortex and the periphery. This neural modulation occurs through synaptic plasticity in the motor cortex. Increase of synaptic efficacy in existing neural circuits, in the form of long-term potentiation (LTP), is proposed to be involved in earlier stages of motor learning. It is suggested that the retention of motor skills involves formation of new synapses.

摘要

本文讨论了支持新运动技能习得的神经机制。在这种情况下,运动学习被定义为新运动技能的习得。有人提出,复杂运动技能是通过分段运动学习过程获得的,在这个过程中形成运动片段,并检索这些片段以执行所学技能。单个运动片段是通过调节连接运动皮层和外周的环路中的神经活动来创建的。这种神经调节通过运动皮层中的突触可塑性发生。以长时程增强 (LTP) 形式存在的现有神经回路中突触效能的增加被认为参与了运动学习的早期阶段。有人认为运动技能的保留涉及新突触的形成。

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