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妇科肿瘤学中盆腔廓清术的当前进展

Current developments for pelvic exenteration in gynecologic oncology.

作者信息

Schneider Achim, Köhler Christhardt, Erdemoglu Evrim

机构信息

Department of Gynecology and Gynecologic Oncology, Campus Benjamin Franklin and Campus Mitte Charité, Germany.

出版信息

Curr Opin Obstet Gynecol. 2009 Feb;21(1):4-9. doi: 10.1097/GCO.0b013e32831c8436.

Abstract

PURPOSE OF REVIEW

The present review aims to update new techniques of pelvic exenteration including minimal invasive surgery, and discuss other aspects of this radical surgery, including worldwide differences.

RECENT FINDINGS

Major advances are made since the first description of pelvic exenteration and the operation is still under evolution. Explorative laparoscopy prior to exenteration is a valuable alternative to laparotomy to elect candidates for pelvic exenteration. There are considerable differences with respect to indications, contraindications, preoperative staging and adjuvant therapy after exenteration in different countries. Advances in laparoscopic instruments also led to the laparoscopic exenteration. The main limiting step of the operation is urinary diversion. New techniques of laparoscopic-assisted and robotic-assisted techniques of urinary diversion have been reported that decrease the operation time. Vascularized muscle flaps are preferred by many surgeons to fill the empty pelvis and provide an acceptable vaginal reconstruction. J-pouch seems to be a safer technique than end-to-end coloanal anastomosis for bowel reconstruction. Developments in the bioengineering tissue for pelvic reconstruction are required.

SUMMARY

Laparoscopy has the advantages of decreased blood loss, improved convalescence, lower incidence of wound infection and incisional hernia, short recovery periods, rapid return of bowel function, better pain control and improved cosmetics compared with laparotomy for pelvic exenteration. Magnification and improved visualization permits en-bloc dissection of tumor and good anastomosis technique. New techniques of urinary diversion, orthotopic neobladder and coloanal are promising.

摘要

综述目的

本综述旨在更新盆腔脏器清除术的新技术,包括微创手术,并讨论这种根治性手术的其他方面,包括全球差异。

最新发现

自首次描述盆腔脏器清除术以来已取得重大进展,且该手术仍在不断发展。在进行盆腔脏器清除术前进行探索性腹腔镜检查是一种有价值的替代剖腹手术的方法,可用于选择盆腔脏器清除术的候选人。不同国家在适应症、禁忌症、术前分期和术后辅助治疗方面存在相当大的差异。腹腔镜器械的进步也促成了腹腔镜盆腔脏器清除术的出现。该手术的主要限制步骤是尿路改道。已有报道称腹腔镜辅助和机器人辅助尿路改道新技术可缩短手术时间。许多外科医生更喜欢使用带血管蒂肌瓣来填充盆腔并提供可接受的阴道重建。对于肠道重建,J形袋似乎比端端结肠肛管吻合术更安全。需要在生物工程组织用于盆腔重建方面取得进展。

总结

与盆腔脏器清除术的剖腹手术相比,腹腔镜手术具有失血减少、康复改善、伤口感染和切口疝发生率降低、恢复时间短、肠功能恢复快、疼痛控制更好以及美容效果更佳等优点。放大和改善的可视化效果有助于整块切除肿瘤并采用良好的吻合技术。尿路改道、原位新膀胱和结肠肛管的新技术很有前景。

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