Patel Manesh R, Dehmer Gregory J, Hirshfeld John W, Smith Peter K, Spertus John A, Masoudi Frederick A, Brindis Ralph G, Beckman Karen J, Chambers Charles E, Ferguson T Bruce, Garcia Mario J, Grover Frederick L, Holmes David R, Klein Lloyd W, Limacher Marian, Mack Michael J, Malenka David J, Park Myung H, Ragosta Michael, Ritchie James L, Rose Geoffrey A, Rosenberg Alan B, Shemin Richard J, Weintraub William S, Wolk Michael J, Allen Joseph M, Douglas Pamela S, Hendel Robert C, Peterson Eric D
Division of Cardiology, Duke University Medical Center, Durham, NC, USA.
Catheter Cardiovasc Interv. 2009 Feb 15;73(3):E1-24. doi: 10.1002/ccd.21964.
The American College of Cardiology Foundation (ACCF), Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, and the American Association for Thoracic Surgery, along with key specialty and subspecialty societies, conducted an appropriateness review of common clinical scenarios in which coronary revascularization is frequently considered. The clinical scenarios were developed to mimic common situations encountered in everyday practice and included information on symptom status, extent of medical therapy, risk level as assessed by noninvasive testing, and coronary anatomy. Approximately 180 clinical scenarios were developed by a writing committee and scored by a separate technical panel on a scale of 1 to 9. Scores of 7 to 9 indicate that revascularization was considered appropriate and likely to improve health outcomes or survival. Scores of 1 to 3 indicate revascularization was considered inappropriate and unlikely to improve health outcomes or survival. The mid range (4 to 6) indicates a clinical scenario for which the likelihood that coronary revascularization would improve health outcomes or survival was considered uncertain. For the majority of the clinical scenarios, the panel only considered the appropriateness of revascularization irrespective of whether this was accomplished by percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG). In a select subgroup of clinical scenarios in which revascularization is generally considered appropriate, the appropriateness of PCI and CABG individually as the primary mode of revascularization was considered. In general, the use of coronary revascularization for patients with acute coronary syndromes and combinations of significant symptoms and/or ischemia was viewed favorably. In contrast, revascularization of asymptomatic patients or patients with low-risk findings on noninvasive testing and minimal medical therapy were viewed less favorably. It is anticipated that these results will have an impact on physician decision making and patient education regarding expected benefits from revascularization and will help guide future research.
美国心脏病学会基金会(ACCF)、心血管造影和介入学会、胸外科医师学会以及美国胸外科协会,联合主要的专科和亚专科协会,对冠状动脉血运重建常被考虑的常见临床情况进行了适用性审查。这些临床情况旨在模拟日常实践中遇到的常见情形,包括症状状态、药物治疗程度、通过无创检测评估的风险水平以及冠状动脉解剖结构等信息。一个写作委员会制定了大约180种临床情况,并由一个独立的技术小组按照1至9的等级进行评分。7至9分表明血运重建被认为是合适的,且可能改善健康结果或生存率。1至3分表明血运重建被认为是不合适的,且不太可能改善健康结果或生存率。中间范围(4至6)表明冠状动脉血运重建改善健康结果或生存率的可能性被认为不确定。对于大多数临床情况,该小组仅考虑血运重建的适用性,而不考虑这是通过经皮冠状动脉介入治疗(PCI)还是冠状动脉旁路移植术(CABG)来完成的。在一般认为血运重建合适的特定临床情况亚组中,分别考虑了PCI和CABG作为主要血运重建方式的适用性。总体而言,对于急性冠状动脉综合征患者以及有明显症状和/或缺血合并症的患者,冠状动脉血运重建的使用受到认可。相比之下,对于无症状患者或无创检测结果为低风险且药物治疗极少的患者,血运重建则不太被看好。预计这些结果将对医生在血运重建预期益处方面的决策以及患者教育产生影响,并将有助于指导未来的研究。