J Am Coll Cardiol. 2014 Feb 4;63(4):380-406. doi: 10.1016/j.jacc.2013.11.009. Epub 2013 Dec 16.
The American College of Cardiology Foundation along with key specialty and subspecialty societies, conducted an appropriate use review of common clinical presentations for stable ischemic heart disease (SIHD) to consider use of stress testing and anatomic diagnostic procedures. This document reflects an updating of the prior Appropriate Use Criteria (AUC) published for radionuclide imaging (RNI), stress echocardiography (Echo), calcium scoring, coronary computed tomography angiography (CCTA), stress cardiac magnetic resonance (CMR), and invasive coronary angiography for SIHD. This is in keeping with the commitment to revise and refine the AUC on a frequent basis. A major innovation in this document is the rating of tests side by side for the same indication. The side-by-side rating removes any concerns about differences in indication or interpretation stemming from prior use of separate documents for each test. However, the ratings were explicitly not competitive rankings due to the limited availability of comparative evidence, patient variability, and range of capabilities available in any given local setting. The indications for this review are limited to the detection and risk assessment of SIHD and were drawn from common applications or anticipated uses, as well as from current clinical practice guidelines. Eighty clinical scenarios were developed by a writing committee and scored by a separate rating panel on a scale of 1 to 9, to designate Appropriate, May Be Appropriate, or Rarely Appropriate use following a modified Delphi process following the recently updated AUC development methodology. The use of some modalities of testing in the initial evaluation of patients with symptoms representing ischemic equivalents, newly diagnosed heart failure, arrhythmias, and syncope was generally found to be Appropriate or May Be Appropriate, except in cases where low pre-test probability or low risk limited the benefit of most testing except exercise electrocardiogram (ECG). Testing for the evaluation of new or worsening symptoms following a prior test or procedure was found to be Appropriate. In addition, testing was found to be Appropriate or May Be Appropriate for patients within 90 days of an abnormal or uncertain prior result. Pre-operative testing was rated Appropriate or May Be Appropriate only for patients who had poor functional capacity and were undergoing vascular or intermediate risk surgery with 1 or more clinical risk factors or an organ transplant. The exercise ECG was suggested as an Appropriate test for cardiac rehabilitation clearance or for exercise prescription purposes. Testing in asymptomatic patients was generally found to be Rarely Appropriate, except for calcium scoring and exercise testing in intermediate and high-risk individuals and either stress or anatomic imaging in higher-risk individuals, which were all rated as May Be Appropriate. All modalities of follow-up testing after a prior test or percutaneous coronary intervention (PCI) within 2 years and within 5 years after coronary artery bypass graft (CABG) in the absence of new symptoms were rated Rarely Appropriate. Pre-operative testing for patients with good functional capacity, prior normal testing within 1 year, or prior to low-risk surgery also were found to be Rarely Appropriate. Imaging for an exercise prescription or prior to the initiation of cardiac rehabilitation was Rarely Appropriate except for cardiac rehabilitation clearance for heart failure patients.
美国心脏病学会基金会与主要专业和亚专业学会合作,对稳定型缺血性心脏病(SIHD)的常见临床表现进行了适当性使用审查,以考虑使用应激试验和解剖学诊断程序。本文件反映了先前发布的放射性核素成像(RNI)、应激超声心动图(Echo)、钙评分、冠状动脉计算机断层血管造影(CCTA)、应激心脏磁共振(CMR)和 SIHD 血管造影的适当使用标准(AUC)的更新。这符合经常修订和完善 AUC 的承诺。本文的一个主要创新是对同一适应症的测试进行并排评级。并排评级消除了因每个测试使用单独的文件而导致的适应症或解释差异的任何担忧。然而,由于比较证据有限、患者变异性以及在任何给定的本地设置中可用的能力范围,这些评级并不是竞争性排名。本审查的适应症仅限于 SIHD 的检测和风险评估,并取自常见的应用或预期用途,以及当前的临床实践指南。一个写作委员会制定了 80 个临床场景,并由一个单独的评分小组根据修改后的 Delphi 流程进行评分,评分范围为 1 到 9,以指定适当、可能适当或很少适当的使用,这是在最近更新的 AUC 开发方法之后进行的。除了在低术前概率或低风险限制大多数测试(除运动心电图 [ECG] 外)获益的情况下,在代表缺血等效物、新诊断心力衰竭、心律失常和晕厥的患者的初始评估中使用某些测试方式被普遍认为是适当或可能适当的。在先前的测试或程序之后,对新出现或恶化的症状进行评估时,测试被认为是适当的。此外,对于在先前异常或不确定结果后 90 天内的患者,测试被认为是适当或可能适当的。仅当患者功能容量差且正在接受血管或中危手术并具有 1 个或多个临床危险因素或器官移植时,术前测试才被评为适当或可能适当。运动心电图被建议用于心脏康复清除或运动处方目的。在无症状患者中,一般认为很少适当,除了中高危人群的钙评分和运动试验,以及高危人群的应激或解剖成像,这些都被评为可能适当。在 2 年内和冠状动脉旁路移植术(CABG)后 5 年内,对先前的测试或经皮冠状动脉介入治疗(PCI)进行的所有后续测试均被评为很少适当。对于功能容量良好的患者,在 1 年内有正常的先前测试或进行低风险手术的患者,也被认为是很少适当的。除了心力衰竭患者的心脏康复清除外,用于运动处方或在开始心脏康复之前的成像也被认为很少适当。