五氟利多对大鼠纹状体和黑质中多巴胺敏感腺苷酸环化酶的影响。
Effects of penfluridol of dopamine-sensitive adenylate cyclase in corpus striatum and substantia nigra of rats.
作者信息
Seeber U, Kuschinsky K
出版信息
Experientia. 1976 Dec 15;32(12):1558-9. doi: 10.1007/BF01924451.
PMID:191279
Abstract
Penfluridol, a neuroleptic with diphenylbutyl piperidine structure, blocked the dopamine-sensitive adenylate cyclase in homogenates of corpus striatum and substantia nigra of rats, probably by a competitive antagonism versus dopamine.
摘要
五氟利多是一种具有二苯基丁基哌啶结构的抗精神病药，它可能通过对多巴胺的竞争性拮抗作用，阻断大鼠纹状体和黑质匀浆中对多巴胺敏感的腺苷酸环化酶。
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