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A case of maternal herpes simplex virus encephalitis during late pregnancy.

作者信息

Sellner Johann, Buonomano Roberto, Nedeltchev Krassen, Findling Oliver, Schroth Gerhard, Surbek Daniel V, Leib Stephen L

机构信息

Department of Neurology, Klinikum rechts der Isar at the Technical University of Munich, Munich, Germany.

出版信息

Nat Clin Pract Neurol. 2009 Jan;5(1):51-6. doi: 10.1038/ncpneuro0972.

Abstract

BACKGROUND

A pregnant 25-year-old woman at 32 weeks' gestation was admitted to an emergency unit after her husband had found her drowsy and with her tongue bitten. The day before admission, the patient had developed a fever of 39 degrees C, was suffering from headaches, was nauseated and had vomited. On admission, she had anterograde and retrograde amnesia, but no somatic neurological deficits were detected.

INVESTIGATIONS

Routine laboratory testing, lumbar puncture, cerebrospinal fluid analysis, routine bacteriology, brain MRI, and polymerase chain reaction testing for neurotropic viruses including herpes simplex virus types 1 and 2.

DIAGNOSIS

Maternal herpes simplex virus type 1 encephalitis.

MANAGEMENT

Antiviral and anticonvulsive therapy, supportive treatment, and cesarean section.

摘要

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