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转移性睾丸畸胎瘤化疗后的手术治疗

Surgery following chemotherapy for metastatic testicular teratoma.

作者信息

Whillis D, Coleman R E, Lessells A M, Hargreave T B, Cornbleet M A, Howard G C

机构信息

Department of Clinical Oncology, Western General Hospital, Edinburgh.

出版信息

Br J Urol. 1991 Sep;68(3):292-5. doi: 10.1111/j.1464-410x.1991.tb15326.x.

DOI:10.1111/j.1464-410x.1991.tb15326.x
PMID:1913071
Abstract

Twenty patients with metastatic testicular teratoma underwent surgery for residual disease after chemotherapy. Twelve patients in whom complete excision of all residual masses was possible are alive with no evidence of disease. Four patients have died of malignant teratoma, 2 have active malignant disease and 2 have inoperable residual cystic disease. Patients with malignant teratoma intermediate (MTI) primary testis tumours, and those with bulky abdominal disease at presentation, are more likely to have residual masses requiring excision. Completeness of excision appears to be the most important predictor of disease-free survival.

摘要

20例转移性睾丸畸胎瘤患者在化疗后接受了残留病灶手术。12例能够完全切除所有残留肿块的患者存活,无疾病证据。4例患者死于恶性畸胎瘤,2例有活动性恶性疾病,2例有无法手术切除的残留囊性疾病。原发性睾丸肿瘤为恶性畸胎瘤中期(MTI)以及初诊时腹部病灶较大的患者,更有可能有需要切除的残留肿块。切除的完整性似乎是无病生存的最重要预测因素。

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引用本文的文献

1
A Scottish national mortality study assessing cause of death, quality of and variation in management of patients with testicular non-seminomatous germ-cell tumours. The Scottish Radiological Society and the Scottish Standing Committee of the Royal College of Radiologists.一项苏格兰全国性死亡率研究,评估睾丸非精原细胞瘤生殖细胞肿瘤患者的死因、治疗质量及差异。苏格兰放射学会和皇家放射科医师学院苏格兰常务委员会。
Br J Cancer. 1995 Nov;72(5):1307-11. doi: 10.1038/bjc.1995.506.
2
A Scottish national audit of current patterns of management for patients with testicular non-seminomatous germ-cell tumours. The Scottish Radiological Society and the Scottish Committee of the Royal College of Radiologists.一项关于睾丸非精原细胞瘤患者当前管理模式的苏格兰全国性审计。苏格兰放射学会和皇家放射科医师学院苏格兰委员会。
Br J Cancer. 1995 Nov;72(5):1303-6. doi: 10.1038/bjc.1995.505.