Whillis D, Coleman R E, Lessells A M, Hargreave T B, Cornbleet M A, Howard G C
Department of Clinical Oncology, Western General Hospital, Edinburgh.
Br J Urol. 1991 Sep;68(3):292-5. doi: 10.1111/j.1464-410x.1991.tb15326.x.
Twenty patients with metastatic testicular teratoma underwent surgery for residual disease after chemotherapy. Twelve patients in whom complete excision of all residual masses was possible are alive with no evidence of disease. Four patients have died of malignant teratoma, 2 have active malignant disease and 2 have inoperable residual cystic disease. Patients with malignant teratoma intermediate (MTI) primary testis tumours, and those with bulky abdominal disease at presentation, are more likely to have residual masses requiring excision. Completeness of excision appears to be the most important predictor of disease-free survival.
20例转移性睾丸畸胎瘤患者在化疗后接受了残留病灶手术。12例能够完全切除所有残留肿块的患者存活,无疾病证据。4例患者死于恶性畸胎瘤,2例有活动性恶性疾病,2例有无法手术切除的残留囊性疾病。原发性睾丸肿瘤为恶性畸胎瘤中期(MTI)以及初诊时腹部病灶较大的患者,更有可能有需要切除的残留肿块。切除的完整性似乎是无病生存的最重要预测因素。