晚期睾丸生殖细胞肿瘤化疗后睾丸原位癌持续存在。
Persistent carcinoma in situ of the testis after chemotherapy for advanced testicular germ cell tumours.
作者信息
Bottomley D, Fisher C, Hendry W F, Horwich A
机构信息
Department of Histopathology, Royal Marsden Hospital, Sutton.
出版信息
Br J Urol. 1990 Oct;66(4):420-4. doi: 10.1111/j.1464-410x.1990.tb14966.x.
The chemosensitivity of testicular carcinoma in situ (CIS) was analysed in 25 testes excised 10 weeks to 4.5 years following platinum-based chemotherapy. CIS was present in 8 of the 23 evaluable cases (35%), in 5 of which the lesion coexisted with invasive germ cell tumour. It is concluded that CIS may persist or recur after chemotherapy. This has implications for occult presentation of metastatic germ cell tumours and also for the management of the contralateral testis in patients with testicular germ cell tumours.
对25例在铂类化疗后10周-4.5年切除的睾丸进行了原位癌（CIS）的化疗敏感性分析。23例可评估病例中有8例存在CIS（35%），其中5例病变与浸润性生殖细胞肿瘤共存。结论是CIS在化疗后可能持续存在或复发。这对转移性生殖细胞肿瘤的隐匿性表现以及睾丸生殖细胞肿瘤患者对侧睾丸的处理都有影响。
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