Nussinov R
Laboratory of Mathematical Biology, NCI, NIH, Bethesda, MD 20892.
Comput Appl Biosci. 1991 Jul;7(3):287-93. doi: 10.1093/bioinformatics/7.3.287.
Biologically occurring nucleotide sequences differ from randomly generated ones. Here we describe general patterns found in prokaryotic and in eukaryotic DNA. In the accompanying paper (Nussinov, 1991) we also describe DNA signals recognized by their corresponding protein factors. In particular, we focus on modes of searches for such patterns and signals and on the potential properties such sequences may possess.
生物产生的核苷酸序列与随机生成的序列不同。在此我们描述原核生物和真核生物DNA中发现的一般模式。在随附的论文(努西诺夫,1991年)中,我们还描述了被其相应蛋白质因子识别的DNA信号。特别地,我们专注于寻找此类模式和信号的方式以及此类序列可能具有的潜在特性。