黄曲霉内生性眼内炎-农民肺疾病后的良好视觉预后。
Excellent visual outcome following Aspergillus flavus endogenous endophthalmitis-farmer's lung disease.
作者信息
Bakri Sophie J, Sears Jonathan E, Procop Gary W, Shrestha Rabin, Gordon Steven M
机构信息
Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905, USA.
出版信息
Int Ophthalmol. 2010 Feb;30(1):99-101. doi: 10.1007/s10792-008-9289-0. Epub 2009 Jan 9.
INTRODUCTION
The purpose is to report an eye with endogenous Aspergillus flavus endophthalmitis that achieved a good visual outcome following early and aggressive management.
METHODS
A 76-year-old male recently hospitalized for allergic Aspergillus pneumonitis after cleaning out a grain bin presented with reduced vision and anterior chamber and vitreous inflammation. The patient was treated with intravenous amphotericin and a pars plana vitrectomy with intravitreal amphotericin, and the vitreous biopsy sent for histopathological and microbial analysis.
RESULTS
A. flavus was isolated from the vitreous biopsy. Two weeks after vitrectomy, intravitreal amphotericin was again injected into the affected eye. The patient regained vision to 20/80 several months later, despite a moderate cataract.
CONCLUSION
Early treatment of A. flavus endophthalmitis with pars plana vitrectomy, intravitreal and systemic amphotericin can lead to good visual outcomes.
引言
目的是报告一例经早期积极治疗后获得良好视力预后的内源性黄曲霉性眼内炎病例。
方法
一名76岁男性，在清理谷仓后因过敏性曲霉菌性肺炎近期住院，出现视力下降以及前房和玻璃体炎症。患者接受了静脉注射两性霉素治疗，并进行了玻璃体切割联合玻璃体内注射两性霉素，玻璃体活检标本送去做组织病理学和微生物分析。
结果
玻璃体活检分离出黄曲霉。玻璃体切割术后两周，再次向患眼玻璃体内注射两性霉素。尽管有中度白内障，患者几个月后视力恢复到20/80。
结论
早期采用玻璃体切割术、玻璃体内及全身应用两性霉素治疗黄曲霉性眼内炎可取得良好的视力预后。
Zotero 插件