Gagliardi T B, Iwamoto M A, Paula F E, Proença-Modena J L, Saranzo A M, Criado M F, Acrani G O, Camara A A, Cintra O A L, Arruda E
Department of Cell Biology, University of Sao Paulo School of Medicine, Ribeirão Preto, SP, Brazil.
Epidemiol Infect. 2009 Jul;137(7):1032-6. doi: 10.1017/S0950268808001842. Epub 2009 Jan 12.
Human bocavirus (HBoV) was recently identified in respiratory samples from patients with acute respiratory infections and has been reported in different regions of the world. To the best of our knowledge, HBoV has never been reported in respiratory infections in Brazil. Nasopharyngeal aspirates were collected from patients aged <5 years hospitalized in 2005 with respiratory infections in Ribeirão Preto, southeast Brazil, and tested by polymerase chain reaction (PCR) for HBoV. HBoV-positive samples were further tested by PCR for human respiratory syncytial virus, human metapneumovirus, human coronaviruses 229E and OC43, human influenza viruses A and B, human parainfluenza viruses 1, 2 and 3, human rhinovirus and human adenovirus. HBoV was detected in 26/248 (10.5%) children of which 21 (81%) also tested positive for other respiratory viruses. Despite the high rates of co-infections, no significant differences were found between HBoV-positive patients with and without co-infections with regard to symptoms.
人博卡病毒（HBoV）最近在急性呼吸道感染患者的呼吸道样本中被发现，且在世界不同地区均有报道。据我们所知，巴西尚未有HBoV在呼吸道感染中被报道的相关情况。2005年，从巴西东南部里贝朗普雷图市因呼吸道感染住院的5岁以下儿童中采集鼻咽抽吸物，并用聚合酶链反应（PCR）检测HBoV。对HBoV阳性样本进一步用PCR检测人呼吸道合胞病毒、人偏肺病毒、人冠状病毒229E和OC43、甲型和乙型人流感病毒、1型、2型和3型人副流感病毒、人鼻病毒和人腺病毒。在248名儿童中有26名（10.5%）检测出HBoV，其中21名（81%）同时也检测出其他呼吸道病毒呈阳性。尽管合并感染率很高，但在有和没有合并感染的HBoV阳性患者之间，症状方面未发现显著差异。
