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印度急性呼吸道感染患儿的人博卡病毒感染。

Human bocavirus infection in children with acute respiratory tract infection in India.

机构信息

Department of Microbiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

出版信息

J Med Virol. 2010 May;82(5):812-6. doi: 10.1002/jmv.21637.

DOI:10.1002/jmv.21637
PMID:20336746
Abstract

Human bocavirus (HBoV) is a new human parvovirus identified in children with respiratory tract disease. Nasopharyngeal aspirates were collected from 305 children <5 years of age with acute respiratory tract infection from April 2005 to March 2007 and screened for the presence of HBoV by two separate sets of a polymerase chain reaction (PCR) described previously. Twenty-two (7.2%) children who had acute respiratory infection were found to be positive for HBoV by both sets of PCR. The main clinical symptoms were cough (95%), runny nose (64%), and fever (59%). In two samples, HBoV was identified together with respiratory syncytial virus in one sample and influenza A virus in another. HBoV appeared to have no seasonal distribution and is associated with both upper and lower respiratory tract disease in young children in India.

摘要

人博卡病毒(HBoV)是一种新发现的人类细小病毒,在患有呼吸道疾病的儿童中被鉴定出来。从 2005 年 4 月至 2007 年 3 月,采集了 305 名年龄在 5 岁以下的急性呼吸道感染儿童的鼻咽抽吸物,并通过之前描述的两组聚合酶链反应(PCR)来筛查 HBoV 的存在。用两组 PCR 都发现,22 名(7.2%)患有急性呼吸道感染的儿童 HBoV 呈阳性。主要临床症状为咳嗽(95%)、流鼻涕(64%)和发烧(59%)。在两个样本中,HBoV 与呼吸道合胞病毒在一个样本中,与甲型流感病毒在另一个样本中共同被鉴定出来。HBoV 似乎没有季节性分布,与印度幼儿的上呼吸道和下呼吸道疾病都有关联。

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