Leung F, Terzibachian J J, Govyadovskiy A, Bourtembourg A, Aouar Z, Fat B C, Maillet R, Riethmuller D
Service de chirurgie gynécologique, CHU Saint-Jacques, 2, place Saint-Jacques, 25000 Besançon, France.
J Gynecol Obstet Biol Reprod (Paris). 2009 Apr;38(2):173-8. doi: 10.1016/j.jgyn.2008.11.005. Epub 2009 Jan 8.
Carcinosarcomas are rare uterine cancers and carry poor prognosis. Although these tumours usually arise de novo, some cases developed under tamoxifen therapy have been reported. We report two more cases of uterine carcinosarcoma occurring in two postmenopausal patients benefiting from tamoxifen therapy as adjuvant treatment of breast cancer. A review of the literature is undertaken.
癌肉瘤是一种罕见的子宫癌,预后较差。尽管这些肿瘤通常是新发的,但已有报道称有些病例是在他莫昔芬治疗期间发生的。我们报告了另外两例子宫癌肉瘤病例,这两名绝经后患者因乳腺癌接受他莫昔芬辅助治疗而发病。本文还对相关文献进行了综述。