一名接受他莫昔芬治疗的患者发生子宫黏液样平滑肌肉瘤：病例报告

Myxoid leiomyosarcoma of the uterus in a patient receiving tamoxifen therapy: a case report.

作者信息

Botsis Dimitris, Koliopoulos Carolina, Kondi-Pafitis Agathi, Creatsas George

机构信息

Second Department of Obstetrics and Gynecology, University of Athens, Areteion University Hospital, Athens, Greece.

出版信息

Int J Gynecol Pathol. 2006 Apr;25(2):173-5. doi: 10.1097/01.pgp.0000185407.93308.ce.

DOI:10.1097/01.pgp.0000185407.93308.ce

PMID:16633068

Abstract

In this paper, we present a case of myxoid leiomyosarcoma development in a patient receiving tamoxifen for 3 years because of breast cancer. The myxoid leiomyosarcoma should be included in the differential diagnosis of any uterine tumor with a predominantly myxomatous composition. A review of the literature indicates that tamoxifen may increase not only the risk for endometrial cancer but also for uterine sarcoma, suggesting vigilance for uterine cancer in women who are being treated with this drug.

摘要

在本文中，我们报告了一例因乳腺癌接受他莫昔芬治疗3年的患者发生黏液样平滑肌肉瘤的病例。黏液样平滑肌肉瘤应纳入任何以黏液瘤样成分为主的子宫肿瘤的鉴别诊断中。文献综述表明，他莫昔芬不仅可能增加子宫内膜癌的风险，还可能增加子宫肉瘤的风险，这提示在接受该药治疗的女性中要警惕子宫癌。