Cancer Genet Cytogenet. 1991 Aug;55(1):101-5.
Isochromosome(21q) is a rare but non-random karyotypic change in hematologic diseases. We report 15 cases of i(21q) among a large group of cases, in various disorders of both myeloid and lymphoid lineage. This abnormality has been found as the sole chromosome change in two cases, the remaining cases exhibiting more or less complex karyotypes. Finally we discuss the labelling "i(21q)".
等臂染色体（21q）是血液系统疾病中一种罕见但非随机的核型改变。我们在一大组病例中报告了15例等臂染色体（21q），涉及髓系和淋系的各种疾病。在两例病例中，此异常被发现是唯一的染色体改变，其余病例显示出或多或少复杂的核型。最后我们讨论了“等臂染色体（21q）”这一命名。
